(a)
Interpretation:
The most acidic proton in compound (1) has to be identified; the corresponding conjugate base of structure (2) has to be drawn and justified.
Concept Introduction:
Conjugate acid: Protonated Base that gets results is called conjugate acid of the given base.
In above reaction, the acid
Conjugate Base: Deprotonated Acid that gets results is called conjugate Base of the given Acid.
In above reaction, the base
Flow of electron density: In the acid-base reaction, the flow of electron from high electron density to low density using curved arrow.
Curved arrows: Curved arrows are used to show the direction of electrons movement. It has a tail (the source of electrons, usually lone pair or bonding pair from a sigma or pi-bond) and head (the destination of electrons, usually forming new lone pair on atom or a new bond). Electrons always flow from high electron density to low electron density.
(b)
Interpretation:
Lithium diisopropyl amide (LDA) is an suitable base to deprotonate has to be justified using a quantitative argument based on
Concept Introduction:
Using
Using
(c)
Interpretation:
Mechanism for the conversion of structure (1) to structure (2) has to be drawn.
Concept Introduction:
Flow of electron density: Curved arrow notation: In the acid-base reaction, the flow of electron from high electron density to low density using curved arrow.
Curved arrows: Curved arrows are used to show the direction of electrons movement. It has a tail (the source of electrons, usually lone pair or bonding pair from a sigma or pi-bond) and head (the destination of electrons, usually forming new lone pair on atom or a new bond). Electrons always flow from high electron density to low electron density.
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