Introduction To Genetic Analysis
12th Edition
ISBN: 9781319114787
Author: Anthony J.F. Griffiths, John Doebley, Catherine Peichel, David A. Wassarman
Publisher: W. H. Freeman
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Chapter 3, Problem 16P
Summary Introduction
To determine: The method of derivation of number 6 from the central bar of histogram.
Introduction: The genotype is the genetic constitution of the organism, while the
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Andy and Anne do not have polydactyl. Is it possible for them to have a child with polydactyl? Explain.
Cystic fibrosis is a genetic disease that causes an abnormal production of mucus which in turn can cause damage and infection to the lungs and other organs. In the following pedigree, black indicates all those persons afflicted with cystic fibrosis (square symbols are males, circles are females). There's a healthy couple and they have two children. One is a 23-year-old daughter with cystic fibrosis who is married to a 24-year-old male who is healthy. The other child is a 15-year-old son who is healthy
After studying the pedigree, write a logical hypothesis suggesting the cause of cystic fibrosis in terms of dominant or recessive alleles.
On the basis of your hypothesis, write an appropriate genotype for both of the parents.
Using a Punnett square, what is the probability of the parents having a child with cystic fibrosis?
If the daughter's husband is a carrier of cystic fibrosis, what is the probability that they have a child with cystic fibrosis? Show your Punnett square.
Hemophilia is an X-linked disease associated with the inability to produce specific proteins in the blood-clotting pathway. Shown above is a family pedigree tree in which family members afflicted with the disease are shown with filled-in squares (male) or circles (females). A couple is trying to determine the likelihood of passing on the disease to their future children (represented by the ? symbol above) because the hemophilia runs in the woman’s family
4.Assuming that the woman in the couple is a carrier, what is the probability that the couple’s first son will have hemophilia?
Chapter 3 Solutions
Introduction To Genetic Analysis
Ch. 3 - Prob. 1PCh. 3 - Prob. 2PCh. 3 - Prob. 3PCh. 3 - Prob. 4PCh. 3 - Prob. 5PCh. 3 - Prob. 6PCh. 3 - Prob. 7PCh. 3 - Prob. 8PCh. 3 - Prob. 9PCh. 3 - Prob. 10P
Ch. 3 - Prob. 11PCh. 3 - Prob. 12PCh. 3 - Prob. 13PCh. 3 - Prob. 14PCh. 3 - Prob. 15PCh. 3 - Prob. 16PCh. 3 - Prob. 17PCh. 3 - Prob. 18PCh. 3 - Prob. 19PCh. 3 - Prob. 20PCh. 3 - Prob. 21PCh. 3 - Prob. 22PCh. 3 - Prob. 23PCh. 3 - Prob. 24PCh. 3 - Prob. 25PCh. 3 - Prob. 26PCh. 3 - Prob. 27PCh. 3 - Prob. 28PCh. 3 - Prob. 29PCh. 3 - Prob. 30PCh. 3 - Prob. 31PCh. 3 - Prob. 32PCh. 3 - Prob. 33PCh. 3 - Prob. 34PCh. 3 - Prob. 35PCh. 3 - Prob. 36PCh. 3 - Prob. 37PCh. 3 - Prob. 38PCh. 3 - Prob. 39PCh. 3 - Prob. 40PCh. 3 - Prob. 41PCh. 3 - Prob. 42PCh. 3 - Prob. 43PCh. 3 - Prob. 43.1PCh. 3 - Prob. 43.2PCh. 3 - Prob. 43.3PCh. 3 - Prob. 43.4PCh. 3 - Prob. 43.5PCh. 3 - Prob. 43.6PCh. 3 - Prob. 43.7PCh. 3 - Prob. 43.8PCh. 3 - Prob. 43.9PCh. 3 - Prob. 43.10PCh. 3 - Prob. 43.11PCh. 3 - Prob. 43.12PCh. 3 - Prob. 43.13PCh. 3 - Prob. 43.14PCh. 3 - Prob. 43.15PCh. 3 - Prob. 44PCh. 3 - Prob. 45PCh. 3 - Prob. 46PCh. 3 - Prob. 47PCh. 3 - Prob. 48PCh. 3 - Prob. 49PCh. 3 - Prob. 50PCh. 3 - Prob. 51PCh. 3 - Prob. 52PCh. 3 - Prob. 53PCh. 3 - Prob. 54PCh. 3 - Prob. 55PCh. 3 - Prob. 56PCh. 3 - Prob. 57PCh. 3 - Prob. 58PCh. 3 - Prob. 59PCh. 3 - Prob. 61PCh. 3 - Prob. 62PCh. 3 - Prob. 63PCh. 3 - Prob. 64PCh. 3 - Prob. 65PCh. 3 - Prob. 66PCh. 3 - Prob. 67PCh. 3 - Prob. 70PCh. 3 - Prob. 1GSCh. 3 - Prob. 2GSCh. 3 - Prob. 3GS
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- If Mark (A) and Gelli (O) have three children, which of their three children, Tony (O), Charm (AB), and Reg (A) is adopted? Create a punnett square.arrow_forwardShown above is a family pedigree tree in which family members afflictedwith the disease Haemophilia are shown with filled-in squares (male) or circles (females). A couple is trying to determine the likelihood of passingon the disease to their future children (represented by the ? symbolabove) because the hemophilia runs in the woman’s family. Turner syndrome is a disease in which an individual is bornwith only a single X chromosome. Suppose the woman in thecouple is a carrier for hemophilia and has a child with Turnersyndrome. Would this child have the disease?arrow_forwardFrank and Susan both have freckles but they're firstborn son Lawrence does not demonstrate the characteristics. What are the most likely genotype of Frank Susan and Lawrence?arrow_forward
- From a cross (Xyz) / (xYZ) x (xyz) / (xyz), where X,x, Y,y and Z,z represent alleles of three linked genes whose relative order is unknown, the least frequent classes of progeny are genotype (xyz) / (xyz) and (XYZ) / (xyz). What is the correct relative order of genes X, Y and Z? Answer using lowercase letters separated by a dash (-). Example: x-y-zarrow_forwardTim and Jan both have freckles, but their son Michael does not. Show with a Punnett square how this is possible. If Tim and Jan have another child, what is the probability that it will have freckles?arrow_forwardAnn's family has a history of cystic fibrosis, a recessive genetic disease. In the pedigree, family members who are afflicted with the disease are shown in red. Members who are unafflicted may or may not be carriers. Which of the given family members can be identified definitively as unafflicted carriers of cystic fibrosis?arrow_forward
- This is a typical pedigree for a family that carries neurofibromatosis. Is individual I-2 most likely homozygous or heterozygous? Why? Explain.arrow_forwardAnn's family has a history of cystic fibrosis, a recessive genetic disease. In the pedigree, family members who are afflicted with the disease are shown in red. Members who are unafflicted may or may not be carriers. Which of the given family members can be identified definitively as unafflicted carriers of cystic fibrosis? Unafflicted carriers Ann Answer Bank father aunt's husband grandmother sister unclearrow_forwardGiven the karyotype shown at right, is this a male or a female? Normal or abnormal? What would the phenotype of this individual be?arrow_forward
- A couple finds out that both the male and the female are heterozygotes (carriers) for Tay Sachs. Draw a punnet square for this couple. What is the likelihood that this couple will have an offspring with Tay Sachs?arrow_forwardJan and Michael are both carriers for the cystic fibrosis allele. If Jan and Michael have three children with the disease and then Jan becomes pregant with fratnernal twins, what is the probability that both twins will also have the disease?arrow_forwardVictoria’s youngest child, Beatrice, gave birth to one daughter, one normal son, and two hemophilic sons. **Based on the pedigree, Alfonso XIII of Spain is phenotypically normal. Does that mean he received the normal gene from Beatrice? Why or Why not?**arrow_forward
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