MOLECULAR BIOLOGY OF THE CELL
MOLECULAR BIOLOGY OF THE CELL
6th Edition
ISBN: 9780393870947
Author: ALBERTS
Publisher: NORTON
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Chapter 3, Problem 11P

A.

Summary Introduction

To explain: Whether the data is consistent with the hypothesis that titin’s spring like behavior is due to the sequential unfolding of individual Ig domains.

Introduction: Protein is a biomolecule. It consists of a chain of amino acids called polypeptide. Titin is a known largest polypeptide. This molecule extends from thick filament of muscle to the Z disc. This acts as spring to keep the thick filament at the center of the sarcomere. Titin is made up of 89 amino acids,. The polypeptide has repeated immunoglobulin sequences.

B.

Summary Introduction

To explain: The putative magnitude in un-folding domain.

Introduction: Protein is a biomolecule. It consists of a chain of amino acids called polypeptide. Titin is a known largest polypeptide. This molecule extends from thick filament of muscle to the Z disc. This acts as spring to keep the thick filament at the center of the sarcomere. Titin is made up of 89 amino acids,. The polypeptide has repeated immunoglobulin sequences.

C.

Summary Introduction

To explain: The reason that the each successive peak in Fig. Q3-2B a little higher than the one before.

Introduction: Protein is a biomolecule. It consists of a chain of amino acids called polypeptide. Titin is a known largest polypeptide. This molecule extends from thick filament of muscle to the Z disc. This acts as spring to keep the thick filament at the center of the sarcomere. Titin is made up of 89 amino acids,. The polypeptide has repeated immunoglobulin sequences.

D.

Summary Introduction

To explain: The reason that the force collapse so abruptly after each peak.

Introduction: Protein is a biomolecule. It consists of a chain of amino acids called polypeptide. Titin is a known largest polypeptide. This molecule extends from thick filament of muscle to the Z disc. This acts as spring to keep the thick filament at the center of the sarcomere. Titin is made up of 89 amino acids,. The polypeptide has repeated immunoglobulin sequences.

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*Example 2: Tracing the path of an autosomal dominant trait Trait: Neurofibromatosis Forms of the trait: The dominant form is neurofibromatosis, caused by the production of an abnormal form of the protein neurofibromin. Affected individuals show spots of abnormal skin pigmentation and non-cancerous tumors that can interfere with the nervous system and cause blindness. Some tumors can convert to a cancerous form. i The recessive form is a normal protein - in other words, no neurofibromatosis.moovi A typical pedigree for a family that carries neurofibromatosis is shown below. Note that carriers are not indicated with half-colored shapes in this chart. Use the letter "N" to indicate the dominant neurofibromatosis allele, and the letter "n" for the normal allele. Nn nn nn 2 nn Nn A 3 N-
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