The reaction conditions that would bind an Fmoc-protected amino acid to a Wang resin are to be proposed. The reaction condition that could be used to remove the polypeptide from the resin after the completion of synthesis is to be predicted. Concept introduction: Peptide linkage is formed between the amino group of one amino acid and the carboxyl group of other amino acid with the loss of water molecule. Amino acids are naturally occurring compounds in which the amino group is present on the alpha carbon of carboxyl group. The full form of Fmoc - Cl is fluorenylmethyloxycarbonyl chloride. It introduces Fmoc group which protects the amine group in organic synthesis .

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Answer 1

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Chapter 29, Problem 29.69P

Interpretation Introduction

Interpretation:

The reaction conditions that would bind an Fmoc-protected amino acid to a Wang resin are to be proposed. The reaction condition that could be used to remove the polypeptide from the resin after the completion of synthesis is to be predicted.

Concept introduction:

Peptide linkage is formed between the amino group of one amino acid and the carboxyl group of other amino acid with the loss of water molecule. Amino acids are naturally occurring compounds in which the amino group is present on the alpha carbon of carboxyl group. The full form of Fmoc -Cl is fluorenylmethyloxycarbonyl chloride. It introduces Fmoc group which protects the amine group in organic synthesis.

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Answer 2

Question

Chapter 29, Problem 29.69P

Interpretation Introduction

Interpretation:

The reaction conditions that would bind an Fmoc-protected amino acid to a Wang resin are to be proposed. The reaction condition that could be used to remove the polypeptide from the resin after the completion of synthesis is to be predicted.

Concept introduction:

Peptide linkage is formed between the amino group of one amino acid and the carboxyl group of other amino acid with the loss of water molecule. Amino acids are naturally occurring compounds in which the amino group is present on the alpha carbon of carboxyl group. The full form of Fmoc -Cl is fluorenylmethyloxycarbonyl chloride. It introduces Fmoc group which protects the amine group in organic synthesis.

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Answer 3

Question

Chapter 29, Problem 29.69P

Interpretation Introduction

Interpretation:

The reaction conditions that would bind an Fmoc-protected amino acid to a Wang resin are to be proposed. The reaction condition that could be used to remove the polypeptide from the resin after the completion of synthesis is to be predicted.

Concept introduction:

Peptide linkage is formed between the amino group of one amino acid and the carboxyl group of other amino acid with the loss of water molecule. Amino acids are naturally occurring compounds in which the amino group is present on the alpha carbon of carboxyl group. The full form of Fmoc -Cl is fluorenylmethyloxycarbonyl chloride. It introduces Fmoc group which protects the amine group in organic synthesis.

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Answer 4

Question

Chapter 29, Problem 29.69P

Interpretation Introduction

Interpretation:

The reaction conditions that would bind an Fmoc-protected amino acid to a Wang resin are to be proposed. The reaction condition that could be used to remove the polypeptide from the resin after the completion of synthesis is to be predicted.

Concept introduction:

Peptide linkage is formed between the amino group of one amino acid and the carboxyl group of other amino acid with the loss of water molecule. Amino acids are naturally occurring compounds in which the amino group is present on the alpha carbon of carboxyl group. The full form of Fmoc -Cl is fluorenylmethyloxycarbonyl chloride. It introduces Fmoc group which protects the amine group in organic synthesis.

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Answer 5

Chapter 29, Problem 29.69P

Interpretation Introduction

Interpretation:

The reaction conditions that would bind an Fmoc-protected amino acid to a Wang resin are to be proposed. The reaction condition that could be used to remove the polypeptide from the resin after the completion of synthesis is to be predicted.

Concept introduction:

Peptide linkage is formed between the amino group of one amino acid and the carboxyl group of other amino acid with the loss of water molecule. Amino acids are naturally occurring compounds in which the amino group is present on the alpha carbon of carboxyl group. The full form of Fmoc -Cl is fluorenylmethyloxycarbonyl chloride. It introduces Fmoc group which protects the amine group in organic synthesis.

Answer 6

Chapter 29, Problem 29.69P

Interpretation Introduction

Interpretation:

The reaction conditions that would bind an Fmoc-protected amino acid to a Wang resin are to be proposed. The reaction condition that could be used to remove the polypeptide from the resin after the completion of synthesis is to be predicted.

Concept introduction:

Peptide linkage is formed between the amino group of one amino acid and the carboxyl group of other amino acid with the loss of water molecule. Amino acids are naturally occurring compounds in which the amino group is present on the alpha carbon of carboxyl group. The full form of Fmoc -Cl is fluorenylmethyloxycarbonyl chloride. It introduces Fmoc group which protects the amine group in organic synthesis.

Answer 7

Chapter 29, Problem 29.69P

Interpretation Introduction

Interpretation:

The reaction conditions that would bind an Fmoc-protected amino acid to a Wang resin are to be proposed. The reaction condition that could be used to remove the polypeptide from the resin after the completion of synthesis is to be predicted.

Concept introduction:

Peptide linkage is formed between the amino group of one amino acid and the carboxyl group of other amino acid with the loss of water molecule. Amino acids are naturally occurring compounds in which the amino group is present on the alpha carbon of carboxyl group. The full form of Fmoc -Cl is fluorenylmethyloxycarbonyl chloride. It introduces Fmoc group which protects the amine group in organic synthesis.

Answer 8

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Answer 11

Ch. 29 - Prob. 29.1P Ch. 29 - Problem 29.2 What form exists at the isoelectric...Ch. 29 - Problem 29.3 Explain why the of the group of an...Ch. 29 - Problem 29.5 What -halo carbonyl compound is...Ch. 29 - Problem 29.6 The enolate derived from diethyl...Ch. 29 - Problem 29.7 What amino acid is formed when is...Ch. 29 - Problem 29.8 What aldehyde is needed to synthesize...Ch. 29 - Prob. 29.8P Ch. 29 - Prob. 29.9P Ch. 29 - Prob. 29.10P

Solution Summary: The author proposes the reaction conditions that would bind an Fmoc-protected amino acid to a Wang resin. The reaction condition that could be used to remove the polypeptide from the resin after the completion of

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