A&P Bundle
11th Edition
ISBN: 9780134761404
Author: Martini
Publisher: PEARSON
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Textbook Question
Chapter 27, Problem 19RQ
What are the three major buffer systems in body fluids? How does each system work?
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Digoxin: Intravenous Bolus - Two Compartment Model
Drug
Digoxin
Route:
IV Bolus
Dose:
0.750 mg
Plasma Concentration Time Profile
Beta
Alpha
Time (hrs)
Conc (ng/ml)
LN
(ng/ml)
LN
(ng/ml)
LN
0.00
#NUM!
#NUM!
#NUM!
0.10
12.290
2.509
#NUM!
#NUMI
0.60
6.975
1.942
#NUM!
#NUMI
1.00
4.649
1.537
#NUM!
#NUMI
2.00
2.201
0.789
#NUM!
#NUM!
3.00
1.536
0.429
#NUM!
#NUM!
4.00
1.342
0.294
#NUM!
#NUM!
5.00
1.273
0.241
#NUM!
#NUMI
6.00
1.238
0.213
#NUM!
#NUM!
7.00
1.212
0.192
#NUM!
#NUM!
8.00
1.188
0.172
#NUMI
#NUM!
9.00
1.165
0.153
#NUM!
#NUMI
10.00
1.143
0.134
#NUMI
#NUM!
11.00
1.122
0.115
#NUM!
12.00
1.101
0.096
#NUMI
13.00
1.080
0.077
#NUMI
16.00
1.020
0.020
#NUMI
24.00
0.876
-0.132
#NUMI
Pharmacokinetic Parameters
Parameter
Value
Alpha
B
Beta
Units
ng/ml
hr-1
ng/ml
hr-1
CO
ng/ml
H.C
AUC
ng x hr/ml
Vc
Vbeta
Vss
C
L/hr
TK (alpha)
hr
TX (beta)
days
5+
F3
F4
F5
0+
F6
F7
%
6
95
14
#3
29
&
t
F8
F9
FW
EW
Chapter 27 Solutions
A&P Bundle
Ch. 27 - Identify the three interrelated processes...Ch. 27 - List the components of extracellular fluid (ECF)...Ch. 27 - Prob. 3CPCh. 27 - Prob. 4CPCh. 27 - Prob. 5CPCh. 27 - Prob. 6CPCh. 27 - Prob. 7CPCh. 27 - Prob. 8CPCh. 27 - Prob. 9CPCh. 27 - Why does prolonged sweating increase the plasma...
Ch. 27 - Prob. 11CPCh. 27 - Identify the bodys three major buffer systems.Ch. 27 - Prob. 13CPCh. 27 - Prob. 14CPCh. 27 - Prob. 15CPCh. 27 - Prob. 16CPCh. 27 - As a person ages, the glomerular filtration rate...Ch. 27 - Prob. 18CPCh. 27 - Prob. 1RQCh. 27 - The principal anions in the ICF are (a) phosphate...Ch. 27 - Prob. 3RQCh. 27 - Prob. 4RQCh. 27 - Calcium homeostasis primarily reflects (a) a...Ch. 27 - Prob. 6RQCh. 27 - Prob. 7RQCh. 27 - Prob. 8RQCh. 27 - Prob. 9RQCh. 27 - Identify four hormones that mediate major...Ch. 27 - Prob. 11RQCh. 27 - Prob. 12RQCh. 27 - Prob. 13RQCh. 27 - Prob. 14RQCh. 27 - Differentiate among fluid balance, electrolyte...Ch. 27 - What are fluid shifts? What is their function, and...Ch. 27 - Prob. 17RQCh. 27 - Define and give an example of (a) a volatile acid,...Ch. 27 - What are the three major buffer systems in body...Ch. 27 - Prob. 20RQCh. 27 - Prob. 21RQCh. 27 - Prob. 22RQCh. 27 - Prob. 23RQCh. 27 - Prob. 24RQCh. 27 - Prob. 25RQCh. 27 - Prob. 26RQCh. 27 - Dan has been lost in the desert for 2 days with...Ch. 27 - Prob. 28RQCh. 27 - Prob. 29RQCh. 27 - Prob. 30RQCh. 27 - Prob. 31RQCh. 27 - Prob. 1CCCh. 27 - Prob. 2CC
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