To identify the compound in the form of which oxaloacetate produced during the citric acid cycle operation enters the urea cycle. Concept introduction: A urea cycle is a cyclic biochemical pathway that involves the production of urea using ammonium ions and aspartate molecules as nitrogen sources. The desired product of the urea cycle is urea. It constitutes 4 steps. In step 1 carbamoyl phosphate transfers its carbamoyl group to ornithine to produce citrulline. Citrulline then condenses with aspartate in the second step to form argininosuccinate which then cleaves in the third step to form arginine and fumarate. In the final step, arginine reacts with water to produce urea. The citric acid cycle is the third stage of the biochemical energy production process. The cycle includes the reactions in which the acetyl part of acetyl CoA is oxidized and leads to the formation of carbon dioxide and CoA − SH .

Question

Consider the following Statements: (1) Citric acid cycle intermediates are often the products from amino acid carbon skeleton degradation. (2) The net effect of transamination is to collect the amino groups from a variety of amino acids into the amino acids glutamate and aspartate. (3) All of the reactions of the urea cycle occur within mitochondria. how many is true

Answer 1

Question

Chapter 26.9, Problem 2QQ

Interpretation Introduction

Interpretation: To identify the compound in the form of which oxaloacetate produced during the citric acid cycle operation enters the urea cycle.

Concept introduction: A urea cycle is a cyclic biochemical pathway that involves the production of urea using ammonium ions and aspartate molecules as nitrogen sources. The desired product of the urea cycle is urea. It constitutes 4 steps. In step 1 carbamoyl phosphate transfers its carbamoyl group to ornithine to produce citrulline. Citrulline then condenses with aspartate in the second step to form argininosuccinate which then cleaves in the third step to form arginine and fumarate. In the final step, arginine reacts with water to produce urea.

The citric acid cycle is the third stage of the biochemical energy production process. The cycle includes the reactions in which the acetyl part of acetyl CoA is oxidized and leads to the formation of carbon dioxide and CoA−SH.

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Consider the following Statements: (1) Citric acid cycle intermediates are often the products from amino acid carbon skeleton degradation. (2) The net effect of transamination is to collect the amino groups from a variety of amino acids into the amino acids glutamate and aspartate. (3) All of the reactions of the urea cycle occur within mitochondria. how many is true

The urea cycle can be summarized through the following reaction: O || H2N-C-OPO3 + COO- | H3N-CHCH₂COO b. O || H2N-C-NH2 1a Write the reactions, using structural formulas that lead to the formation of carbamoyl phosphate and its subsequent incorporation into the urea cycle. Name the enzymes and how they are activated. 1 + OOCCH=CHCOO- Write the rest of the reactions that constitute the urea cycle using structural formulas. Name the enzymes that catalyze each reaction. Indicate which reactions occur in the mitochondrion and which occur in the cytoplasm.

If 14CO2 (radioactive carbon) were incorporated into the TCA cycle via the Pyruvate Carboxylase reaction which of the following molecules would contain radioactive carbon? a. Oxaloacetate b. Citric Acid c. Isocitrate d. Alpha-ketoglutarate e. Succinyl-CoA f .Succinate g. Fumarate h. Malate