A 28-year-old woman was admitted to a Wisconsin hospital with a 1-week history of arthritis of the left knee. Four days later, a 32-year-old man was examined for a 2-week history of urethritis and a swollen, painful left wrist. A 20-year-old woman seen in a Philadelphia hospital had pain in the right knee, left ankle, and left wrist for 3 days. Pathogens cultured from synovial fluid or urethral culture were gram-negative diplococci that required proline to grow. Antibiotic sensitivity tests gave the following results:
Antibiotic | MIC Tested (μg/ml) | Susceptible MIC (μg/ml) | |
Cefoxitin | 0.5 | ≤2 | |
Penicillin | 8 | ≤0.06 | |
Spectinomycin | 64 | ≤32 | |
Tetracycline | 4 | ≤0.25 |
What is the pathogen, and how is this disease transmitted? Which of the antibiotics should be used for treatment? What is the evidence that these cases are related?
Want to see the full answer?
Check out a sample textbook solutionChapter 26 Solutions
Microbiology: An Introduction
Additional Science Textbook Solutions
Campbell Essential Biology with Physiology (6th Edition)
Biology: Concepts and Investigations
Anatomy & Physiology: The Unity of Form and Function
Human Physiology: An Integrated Approach (7th Edition)
Laboratory Experiments in Microbiology (11th Edition)
Human Anatomy (8th Edition)
- Gram positive case on the first day back to class at the local university, a student noticed a small abscess on his right elbow but didn't think much about it. Over the next couple days, however the abscess became more swollen and painful. The student decided to visit the health centet he told the doctor it looked like a spider bite but didn't recall being bitten. The doctor took a swab of the lesion and prescribed an antibiotic cream as it looked infected. The swab was sent to the lab for testing within a few days of treatment, the student lesion was healed. what is the overview of the etiological agent?( including basic characteristics of the organism, diseases it cause and use in industry) Broad to get a sense of what this organism isarrow_forwardThree to five days after eating Thanksgiving dinner at a restaurant, 112 people developed fever and gastroenteritis. The dinner consisted of Roast Turkey, turkey giblet soup, mashed potatoes and crushed giblet gravy. The gravy was not refrigerated and was served the entire Thanksgiving day. The analysis of leftover food showed the same bacteria as was isolated from patients. a) What was the source of illness? b) What was the most likely microbe causing this illness? c) Was this an infection or an intoxication?arrow_forwardThe patient was an 80-year-old female who 10 days previously had had a cystocele repair performed. At the time of the hospital admission, a urine culture was obtained and revealed >100,000 CFU/ml of an Escherichia coli strain that was susceptible to all antimicrobial agents against which it was tested. Postoperatively, she began a 7-day course of oral cephalexin. She was discharged after an uneventful postoperative course of 3 days. Ten days postoperatively, she presented with a 3-day history of diarrhea. The patient noted multiple watery, loose stools without blood, crampy abdominal pain, and vomiting. She presented with a temperature of 38.2 degrees C, pulse rate of 90/min, respiration rate of 20/min, and blood pressure of 116/53mm Hg. Her white blood cell count was normal, but a large number (53%) of immature polymorphonuclear cells were seen. Physical examination, electrolytes, liver enzymes, and lipase were all within normal limits. Cultures for Salmonella, Shigella, Yersinia,…arrow_forward
- I AM TRYING TO IDENTIFY THIS UNKNOWN. IMAGE 1 HAS TWO PICTURE OF CATALASE TEST AND BLOOD AGAR TEST. I believe it is one of the following: 1) S. pyo. 2)S. agal . 3)S.pneu. 4)E. faecalis 5)S. aureus 6)S epi. 7)S. sapro. 8)M. luteus Please let me know which test will i need out of the table to justify your reason of picking up the unknown and also how that test justifies it? what characteristics of that test made you pick the unknown?arrow_forward7-year-old boy is brought to the pediatrician with lesions under his lips as shown in the attached image. Parents report that the lesions developed over the course of a week. On physical examination, his temperature is 37°C, pulse rate is 80/min, blood pressure is 110/80 mmHg, and respiratory rate is 20/min. A culture of the sample from the lesion yields Gram-positive, catalase-negative, cocci. Which of the following is the most likely pathogen? Answers A - E A Candida albicans B Coxsackie A virus C Herpes simplex 1 D Staphylococcus aureus E Streptococcus pyogenes O O O O Question # 33 attachment CLOSE TOOLKIT Qarrow_forwardA 27-year old white female presented at the walking clinic of her local physician on August 15. On physical exam, the patient had a fever of 38.5C. She appeared fatigued, had tender joints, and complained of a headache, a stiff neck and a backache. The physician noticed a circular "rash" about 5 inches in diameter, with a bright red leading edge and a dim center in the form of a "bull's eye." The physician noted an irregular heartbeat. The patient complained of lack of ability to concentrate. The patient gave the following history: She is a graduate student in the wildlife program at the university in town. She was in the field for three weeks in Wisconsin during the months of May and June. She tracks small mammals in the field and studies their behavior. It had been a warm, wet spring and she complained of a large number of biting flies, mosquitoes and ticks in the area. She felt well until about two weeks after returning to her home. Since that time, many of her symptoms had…arrow_forward
- Why does necrotizing fasciitis require immediate surgery?arrow_forwardA 42-year-old woman from coastal Texas comes to her primary care physician with 2 days of fever and malaise. She also says that she has a painful red lesion on her left hand that she noticed after shucking oysters at a recent family reunion. Physical examination reveals a well-demarcated swollen, tender, warm, red lesion on her left hand. Pressing the lesion causes a small amount of purulent drainage. The material is cultured and the causative organism is identified as a gram negative halophilic rod. Which of the following is the etiologic agent? Answers A - E A Actinomyces israelli B Bartonella henselae C Pseudomonas aeruginosa D Streptococcus pyogenes E Vibrio vulnificus O O Oarrow_forwardPlease refer to the given scenario below. What is the most appropriate sample to be collected to isolate the causative agent of the infection? * A 46-year-old male encountered a motor-vehicular accident (MVA) resulting in multiple injuries on his anterior chest and left lower extremities. Aside from the injury, his medical history was unremarkable. The patient was admitted for nine days and underwent debridement and was discharged with an external fixator. However, during his admission, on his 7m post-operative day, the wound was noted to have persistent purulent, bloody discharge from drain site, which is highly suggestive of surgical site infection (SSI). Whole blood Debridement Serum Discharge from drain sitearrow_forward
- A 5 years-old child died from severe septic shock, circulatory collapse following a sudden onset of fever, severe headache and vomiting. The causative agent was isolated from blood and CSF and was Gram-negative that was also identified by latex agglutination. What is the most important virulence factor involved in disease production by the above bacteria?arrow_forwardreview the case uploaded. in a practice scenario to identify unknown bacteria. a) in your own words write an introduction on how you identify unknown bacteriaarrow_forwardHow is L. pneumophila acquired?arrow_forward
- Microbiology for Surgical Technologists (MindTap ...BiologyISBN:9781111306663Author:Margaret Rodriguez, Paul PricePublisher:Cengage LearningComprehensive Medical Assisting: Administrative a...NursingISBN:9781305964792Author:Wilburta Q. Lindh, Carol D. Tamparo, Barbara M. Dahl, Julie Morris, Cindy CorreaPublisher:Cengage LearningUnderstanding Health Insurance: A Guide to Billin...Health & NutritionISBN:9781337679480Author:GREENPublisher:Cengage