Concept explainers
Case summary:
A 23-year-old woman has her first prenatal examination. She is 4 1/4 months pregnant. Her VDRL results showed negative. The woman returns to her physician complaining of a labial lesion of a few days' duration. A biopsy is negative for malignancy, and herpes test results shows negative. The woman returns to her physician because the labial lesion continues to cause some discomfort. The baby's father has multiple penile lesions and a generalized body rash. The woman delivers her baby. Her RPR is 32, and the infant's is 128. The woman takes her infant to a pediatrician because the baby is lethargic. She has been told that the infant is healthy and need not be worried. The baby's father has a persistent body rash and plantar and palmar rashes. The infant becomes acutely ill with pneumonia and is hospitalized. The admitting physician finds the signs of osteochondritis.
Characters of the case
Symptoms: Labial lesion; the father has multiple penile lesions and body rash.
Diagnosis: VDRL negative, no malignancy, herpes test shows negative.
About the disease:
Syphilisis caused byTreponema pallidum. Congenital syphilis can be transmitted to unborn fetus through placenta and affect the mental development and also could lead to death. Antibiotics benzathine penicillin treatment during the first two trimesters can prevent congenital syphilis.
Want to see the full answer?
Check out a sample textbook solutionChapter 26 Solutions
Microbiology: An Introduction
- Answer by listing only the name of the disease or Some questions will require the name of the organism 1.A 10 year old girl presents with a headache and difficulty breathing. Her mother says she's had sporadic fevers for the past week, which has interfered with her sleep. Inspection of her throat showed the presence of a dark gray pseudomembrane in the back of her throat, which prompts you to prescribe penicillin. What condition is the girl suffering from? A 45 year old female presents with a fever, chills, and shortness of breath. She tells you she thinks she has rabies because a squirrel bit her when she was tending to her garden a couple of weeks ago and she still has the mark to prove it. Upon further observation, you have questions since the bite mark you see on her hand looks more like a tick bite and is in the early stages of becoming an ulcer. You notice her lymph nodes in her armpits are larger than normal. What does the patient have?arrow_forwardWhy would using antibiotics predispose a woman to vulvovaginal candidiasis (VVC)?arrow_forwardA man wants to divorce his wife because he believes her genitalherpes could only have been acquired sexually. Her doctor says she isinfected with type 1. Suggest a more likely source.arrow_forward
- Name the disease caused by herpesviruses.arrow_forwardGive the virus etiology of the following : 1. Acute Herpetic Gingivostomatitis 2. Chickenpox 3. Infectious Mononucleosis 4. Herpangina 5. Hand, Foot & Mouth disease 6. Measles 7. Mumps 8. Kaposi’s Sarcomaarrow_forwardA 44-year-old Nigerian man was admitted as an emergency while visiting relatives in England. His symptoms include abdominal pain, sweating, rigors and vomiting. Had been treated twice for malaria but had never taken malarial prophylaxis. Examination revealed he is ill and jaundiced, temperature of 39.2°C, blood pressure was 90/70, but no signs of visceral perforation. Differential diagnosis include– occult gastrointestinal bleeding, septicaemia, hepatitis or recurrence of malaria Emergency investigations: normal haemoglobin (140g/l), white cell count of 6.1 x 109/l, sickle-cell anaemia (excluded), thick blood film Treatment: intravenous quinine. Unfortunately the Px rapidly deteriorated over the next 30h leading to cardiac arrest. Post-mortem diagnosis: Cerebral Malaria QUESTION: 1.What is your final diagnosis here? Explain the cause of his disease. 2. What drug, dosage form, schedule, and duration of therapy are best for treating patients with this condition?arrow_forward
- A 13-year-old male, who recently immigrated with his parents from Romania, presents with a 2 day history of fever, sore throat and difficulty breathing. Immunization records are unavailable. On physical exam, temperature is 102°F (38.9°C). A grayish white membrane is seen in the oropharynx. There is enlargement of the cervical lymph nodes, resulting in a bull neck. QUESTIONS: What pathogen caused the disease? What is the morphology and staining characteristics of the pathogen? What is its most important virulence factor? Discuss: Criteria for toxin production (lysogeny, iron…) Properties of the toxin Mode of action How does the pathogen spread? What risk factors are associated with the infection? What are the clinical symptoms of the disease? What are the possible complications from the disease? How is the disease diagnosed? Discuss: Specimen selection Microscopic observation Culture Virulence test What is the best treatment for the disease? How can the disease be prevented?…arrow_forwardThis 20-year-old college junior came to the student health office because she had been exposed to rubella during a recent outbreak at the college. She was immunized as a child. Laboratory Data Screening procedure for rubella—negative Pregnancy test—positive Ultrasonography shows that the fetus is in the eighth week of development Critical Thinking Group Discussion Questions Is this woman susceptible to rubella infection? Is the fetus at risk of a congenital defect? Is there any treatment for the infection? What are the immunologic manifestations of infection?arrow_forward1. What is the possible condition of the patient?2. Are the leukocyte count and differential count normal?3. What is the probable ethology of this disorder?4. What are the immunologic/serologic manifestations of infection?5. Are there any laboratory test that would further support the infection?arrow_forward
- A fever is considered to be a ____________________________. prognosis sign symptom syndromearrow_forwardComplete the table below by giving a complete description of the following common viral infections in the oral cavity. CLASSIFICATION Viral Etiology DNA or RNA Virus? Oral signs & symptoms Clinical Picture 1. Acute Herpetic Gingivostomatitis 2. Chickenpox 3. Infectious Mononucleosis 4. Herpangina 5. Hand, Foot & Mouth disease 6. Measles 7. Mumps 8. Kaposi’s Sarcomaarrow_forwardName the diagnostic test which confirms typhoid.arrow_forward
- Health Safety And Nutrition F/Young ChildHealth & NutritionISBN:9781305144767Author:MAROTZPublisher:Cengage
- Basic Clinical Lab Competencies for Respiratory C...NursingISBN:9781285244662Author:WhitePublisher:CengageMedical Terminology for Health Professions, Spira...Health & NutritionISBN:9781305634350Author:Ann Ehrlich, Carol L. Schroeder, Laura Ehrlich, Katrina A. SchroederPublisher:Cengage Learning