Study Guide with Student Solutions Manual for McMurry's Organic Chemistry, 9th
Study Guide with Student Solutions Manual for McMurry's Organic Chemistry, 9th
9th Edition
ISBN: 9781305082144
Author: John E. McMurry
Publisher: Cengage Learning
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Chapter 25.SE, Problem 31MP
Interpretation Introduction

Interpretation:

To propose a mechanism of mannose 6-phosphate derivative from fructose 6-phosphate.

Concept introduction:

Acid-base Catalysis by the enzyme.

Step 1: Substrate binding.

Step 2: Acid catalyzed ring opening.

Step 3: Base abstracts the acidic proton from C2 to form a cis enediolete intermediate.

Step 4: proten is replaced on C-1 as ab iverall proton teamster.

Step 5: Ring disuse to form product.

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a) b) c) H NaOH heat, dehydration + KOH heat, dehydration NaOH + (CH3)3CCHO heat, dehydration Ph
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Chapter 25 Solutions

Study Guide with Student Solutions Manual for McMurry's Organic Chemistry, 9th

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