The initial PTH derivative formed when Ala-Phe-Val undergoes Edman degradation need to be drawn. Concept introduction: Edman degradation is a chemical reaction where the N-terminus amino acid is removed when the peptide is treated with phenyl isothiocyanate followed by treatment with trifluoroacetic acid to form phenylthiohydantoin(PTH) derivative and peptide with one amino acid residue less than the starting peptide. This method can be used to identify the sequence of the amino acid in peptide as only one amino acid is removed each time forming the PTH derivative. The general scheme for Edman degradation can be shown as, To draw : the structure of initial PTH derivative obtained when tripeptide Ala-Phe-Val undergoes Edman degradation.

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Answer 1

Question

Chapter 25.5, Problem 30CC

Interpretation Introduction

Interpretation:

The initial PTH derivative formed when Ala-Phe-Val undergoes Edman degradation need to be drawn.

Concept introduction:

Edman degradation is a chemical reaction where the N-terminus amino acid is removed when the peptide is treated with phenyl isothiocyanate followed by treatment with trifluoroacetic acid to form phenylthiohydantoin(PTH) derivative and peptide with one amino acid residue less than the starting peptide. This method can be used to identify the sequence of the amino acid in peptide as only one amino acid is removed each time forming the PTH derivative. The general scheme for Edman degradation can be shown as,

To draw: the structure of initial PTH derivative obtained when tripeptide Ala-Phe-Val undergoes Edman degradation.

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Answer 2

Question

Chapter 25.5, Problem 30CC

Interpretation Introduction

Interpretation:

The initial PTH derivative formed when Ala-Phe-Val undergoes Edman degradation need to be drawn.

Concept introduction:

Edman degradation is a chemical reaction where the N-terminus amino acid is removed when the peptide is treated with phenyl isothiocyanate followed by treatment with trifluoroacetic acid to form phenylthiohydantoin(PTH) derivative and peptide with one amino acid residue less than the starting peptide. This method can be used to identify the sequence of the amino acid in peptide as only one amino acid is removed each time forming the PTH derivative. The general scheme for Edman degradation can be shown as,

To draw: the structure of initial PTH derivative obtained when tripeptide Ala-Phe-Val undergoes Edman degradation.

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Check out a sample textbook solution

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Answer 3

Question

Chapter 25.5, Problem 30CC

Interpretation Introduction

Interpretation:

The initial PTH derivative formed when Ala-Phe-Val undergoes Edman degradation need to be drawn.

Concept introduction:

Edman degradation is a chemical reaction where the N-terminus amino acid is removed when the peptide is treated with phenyl isothiocyanate followed by treatment with trifluoroacetic acid to form phenylthiohydantoin(PTH) derivative and peptide with one amino acid residue less than the starting peptide. This method can be used to identify the sequence of the amino acid in peptide as only one amino acid is removed each time forming the PTH derivative. The general scheme for Edman degradation can be shown as,

To draw: the structure of initial PTH derivative obtained when tripeptide Ala-Phe-Val undergoes Edman degradation.

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Answer 4

Question

Chapter 25.5, Problem 30CC

Interpretation Introduction

Interpretation:

The initial PTH derivative formed when Ala-Phe-Val undergoes Edman degradation need to be drawn.

Concept introduction:

Edman degradation is a chemical reaction where the N-terminus amino acid is removed when the peptide is treated with phenyl isothiocyanate followed by treatment with trifluoroacetic acid to form phenylthiohydantoin(PTH) derivative and peptide with one amino acid residue less than the starting peptide. This method can be used to identify the sequence of the amino acid in peptide as only one amino acid is removed each time forming the PTH derivative. The general scheme for Edman degradation can be shown as,

To draw: the structure of initial PTH derivative obtained when tripeptide Ala-Phe-Val undergoes Edman degradation.

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Answer 5

Chapter 25.5, Problem 30CC

Interpretation Introduction

Interpretation:

The initial PTH derivative formed when Ala-Phe-Val undergoes Edman degradation need to be drawn.

Concept introduction:

Edman degradation is a chemical reaction where the N-terminus amino acid is removed when the peptide is treated with phenyl isothiocyanate followed by treatment with trifluoroacetic acid to form phenylthiohydantoin(PTH) derivative and peptide with one amino acid residue less than the starting peptide. This method can be used to identify the sequence of the amino acid in peptide as only one amino acid is removed each time forming the PTH derivative. The general scheme for Edman degradation can be shown as,

To draw: the structure of initial PTH derivative obtained when tripeptide Ala-Phe-Val undergoes Edman degradation.

Answer 6

Chapter 25.5, Problem 30CC

Interpretation Introduction

Interpretation:

The initial PTH derivative formed when Ala-Phe-Val undergoes Edman degradation need to be drawn.

Concept introduction:

Edman degradation is a chemical reaction where the N-terminus amino acid is removed when the peptide is treated with phenyl isothiocyanate followed by treatment with trifluoroacetic acid to form phenylthiohydantoin(PTH) derivative and peptide with one amino acid residue less than the starting peptide. This method can be used to identify the sequence of the amino acid in peptide as only one amino acid is removed each time forming the PTH derivative. The general scheme for Edman degradation can be shown as,

To draw: the structure of initial PTH derivative obtained when tripeptide Ala-Phe-Val undergoes Edman degradation.

Answer 7

Chapter 25.5, Problem 30CC

Interpretation Introduction

Interpretation:

The initial PTH derivative formed when Ala-Phe-Val undergoes Edman degradation need to be drawn.

Concept introduction:

Edman degradation is a chemical reaction where the N-terminus amino acid is removed when the peptide is treated with phenyl isothiocyanate followed by treatment with trifluoroacetic acid to form phenylthiohydantoin(PTH) derivative and peptide with one amino acid residue less than the starting peptide. This method can be used to identify the sequence of the amino acid in peptide as only one amino acid is removed each time forming the PTH derivative. The general scheme for Edman degradation can be shown as,

To draw: the structure of initial PTH derivative obtained when tripeptide Ala-Phe-Val undergoes Edman degradation.

Answer 8

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Answer 9

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Answer 10

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Answer 11

Ch. 25.2 - Prob. 1CC Ch. 25.2 - Prob. 2CC Ch. 25.2 - Prob. 3CC Ch. 25.2 - Prob. 1LTS Ch. 25.2 - Prob. 4PTS Ch. 25.2 - Prob. 7CC Ch. 25.2 - Prob. 8CC Ch. 25.2 - Prob. 9CC Ch. 25.2 - Prob. 10CC Ch. 25.2 - Prob. 11CC

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Chapter 25 Solutions