BIOCHEMISTRY W/1 TERM ACHEIVE ACCESS
9th Edition
ISBN: 9781319425746
Author: BERG
Publisher: MAC HIGHER
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Question
Chapter 25, Problem 27P
Interpretation Introduction
Interpretation:
Possible treatment for orotic aciduria is to be determined.
Concept introduction:
Orotic aciduria is a disease caused due to the deficiency of UMP synthetase enzyme. The function of this enzyme is to convert orotic acid into UMP (uridine monophosphate). This means, inactivity of the enzyme results in a decreased ability of synthesis of pyrimidines.
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Determine the amount of VRK1 is present
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Macmillan Learning
Cholesterol synthesis begins with the formation of mevalonate from acetyl CoA. This
process activates mevalonate and converts it to isopentenyl pyrophosphate.
Identify the atoms in mevalonate and isopentenyl pyrophosphate that will be labeled
from acetyl CoA labeled with 14C in the carbonyl carbon. Place 14C atoms and C atoms
to denote which carbon atoms are labeled and which are not labeled.
H₂C
COA
14C-labeled acetyl-CoA
HHH
[c]
H
H
OH
014C
- OH
H
HH
H
Mevalonate
CH3
H H
14C
H
Η
H
H
Incorrect Answer
of o
-P-O-P-0-
Isopentenyl pyrophosphate
с
Answer Bank
14C
Chapter 25 Solutions
BIOCHEMISTRY W/1 TERM ACHEIVE ACCESS
Ch. 25 - Prob. 1PCh. 25 - Prob. 2PCh. 25 - Prob. 3PCh. 25 - Prob. 4PCh. 25 - Prob. 5PCh. 25 - Prob. 6PCh. 25 - Prob. 7PCh. 25 - Prob. 8PCh. 25 - Prob. 9PCh. 25 - Prob. 10P
Ch. 25 - Prob. 11PCh. 25 - Prob. 12PCh. 25 - Prob. 13PCh. 25 - Prob. 14PCh. 25 - Prob. 15PCh. 25 - Prob. 16PCh. 25 - Prob. 17PCh. 25 - Prob. 18PCh. 25 - Prob. 19PCh. 25 - Prob. 20PCh. 25 - Prob. 21PCh. 25 - Prob. 22PCh. 25 - Prob. 23PCh. 25 - Prob. 24PCh. 25 - Prob. 25PCh. 25 - Prob. 26PCh. 25 - Prob. 27PCh. 25 - Prob. 28PCh. 25 - Prob. 29PCh. 25 - Prob. 30PCh. 25 - Prob. 31PCh. 25 - Prob. 32PCh. 25 - Prob. 33PCh. 25 - Prob. 34PCh. 25 - Prob. 35PCh. 25 - Prob. 36PCh. 25 - Prob. 37PCh. 25 - Prob. 38PCh. 25 - Prob. 39PCh. 25 - Prob. 40PCh. 25 - Prob. 41PCh. 25 - Prob. 42PCh. 25 - Prob. 43PCh. 25 - Prob. 44PCh. 25 - Prob. 45PCh. 25 - Prob. 46PCh. 25 - Prob. 47PCh. 25 - Prob. 48PCh. 25 - Prob. 49PCh. 25 - Prob. 50PCh. 25 - Prob. 51P
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