Concept explainers
(a)
Interpretation: The carbonyl and nitrogen compounds needed to prepare the given compound using reductive amination are to be determined.
Concept introduction: The conversion of
(b)
Interpretation: The carbonyl and nitrogen compounds needed to prepare the given compound using reductive amination are to be determined.
Concept introduction: The conversion of aldehydes and ketones into amines is known as reductive amination. The first step is the formation of imines using aldehydes or ketones and amines. The second step involves the reduction of imine to form amine. The best reagent for this reaction is sodiumcyanoborohydride.
(c)
Interpretation: The carbonyl and nitrogen compounds needed to prepare the given compound using reductive amination are to be determined.
Concept introduction: The conversion of aldehydes and ketones into amines is known as reductive amination. The first step is the formation of imines using aldehydes or ketones and amines. The second step involves the reduction of imine to form amine. The best reagent for this reaction is sodiumcyanoborohydride.
Want to see the full answer?
Check out a sample textbook solutionChapter 25 Solutions
Organic Chemistry
- Maraviroc, a drug used to treat HIV, is prepared by reductive amination of aldehyde A with amine B. What is the structure of maraviroc, if the most basic N atom of amine B is used in reductive amination?arrow_forwardThe order of increasing acidity is Phenol < meta-cyanophenol < ortho-cyanophenol 1.how about para-cyanophenol??does it has higher acidicity than both ortho-cyanophenol and meta cyanophenol or lower?? 2.why does ortho-cyanophenol have higher acidicity than meta cyanophenol?? 3. why doesmeta cyanophenol have higher acidicity than Phenolarrow_forward12) Which compound is stronger base? a) b) D A d) all the samearrow_forward
- Give detailed Solution with explanation neededarrow_forwardWhat alkyl halide and nucleophile are needed to prepare each compound?arrow_forward16.41) Give on IUPAC or common home for each compound. 2 b. in O d. Hon de jha ok C. e- ion ganho-to- 0 y. ho Y 2-ethylbutonoyl chloride methyl benzoate N-ethyl-N-methylpropion amide ethyl formale benzoic propionic anhydride isopropyl 3-ethyl hexanoatearrow_forward
- Compound that is most easily hydrolyzed by acid in water `NH A. В. F C. D.arrow_forwardWhich compound is stronger base in each set of compounds? a. (i) HOCH2CH2NH2 or (ii)CH3CH2NH2 b. (i) (ii) orarrow_forward2.44 What product is formed when each compound is treated with NaH? Each of these acid-base reactions was a step in a synthesis of a commercially available drug. а. b. С. H2N- OH N.arrow_forward
- Methylparaben is a common preservative used in cosmetics. What carboxylic acid and alcohol are needed to synthesize methylparaben by Fischer esterifi cation?arrow_forwardHow about ortho-cyanophenol ?? does para-cyanophenol have higher acidicity than ortho-cyanophenol or are they equal??arrow_forwardWhat product is formed when A is treated with Grubbs catalyst underhigh-dilution conditions? This reaction was a key step in the synthesis ofstemoamide, the naturally occurring amide described in the opening paragraph.arrow_forward
- Organic ChemistryChemistryISBN:9781305580350Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. FootePublisher:Cengage LearningOrganic Chemistry: A Guided InquiryChemistryISBN:9780618974122Author:Andrei StraumanisPublisher:Cengage Learning