Lehninger Principles of Biochemistry (Instructor's)
7th Edition
ISBN: 9781319117689
Author: nelson
Publisher: MAC HIGHER
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Chapter 25, Problem 11P
Summary Introduction
To determine: The number of base-pairs which will be unwound and replicated by each replication fork before the forks stall during
Introduction:
Most of the cellular DNAs are supercoiled. During replication, the underwinding of the DNA removes some turns, thereby decreasing total number of helical turns. Underwinding of DNA is quantified by linking number denoted by Lk.
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