Lehninger Principles of Biochemistry (Instructor's)
Lehninger Principles of Biochemistry (Instructor's)
7th Edition
ISBN: 9781319117689
Author: nelson
Publisher: MAC HIGHER
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Chapter 25, Problem 16P

(a)

Summary Introduction

To determine: The nucleotide sequence AAC(O6-meG)TGCAC which is methylated at guanine residue with change of this sequence when replication occurs before repair.

Introduction:

Direct repair includes the removal of the formation of thymidine dimers when ultra-violet light is used. This reaction is catalyzed by enzyme DNA photolyase . Methylation of guanine residues takes place in the presence of methylating agents.

(b)

Summary Introduction

To determine: The nucleotide sequence AAC(O6-meG)TGCAC which is methylated at guanine residue with change of this sequence when replication occurs after repair.

Introduction:

Methylation of guanine takes place after addition of chemical which leads to DNA damage.

(c)

Summary Introduction

To determine: The nucleotide sequence AAC(O6-meG)TGCAC which is methylated at guanine residue with two rounds of replication following repair.

Introduction:

Replication process leads to the formation of two strands of DNA which have complementary base pairs present in between them.

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