Organic Chemistry, Books a la Carte Edition (8th Edition)
Organic Chemistry, Books a la Carte Edition (8th Edition)
8th Edition
ISBN: 9780134074580
Author: Bruice, Paula Yurkanis
Publisher: PEARSON
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Chapter 24.9, Problem 20P
Interpretation Introduction

Interpretation:

The steps for α-ketoglutarate to succinyl-CoA conversion has to be drawn.

Concept introduction:

Protein catabolism: It is defined as breakdown of proteins into smaller units that is into amino acids gets transported finally polymerized to give new proteins.

Citric Acid Cycle: It involves 8 series reaction which converts acetyl group present in acetyl coenzyme A into 2 CO2 molecules.

Substrate: The molecule where the reaction takes place with help of enzymes.

Enzyme: The proteins that helps chemical reaction to occur.

Oxidation: The oxidation is reaction that involves addition of oxygen atom or loss of electrons or removal of hydrogen atom present in the chemical compound.

Reduction: It involves removal of oxygen or addition of hydrogen to the chemical compound.

Coenzyme: They are non-proteins molecules which helps enzymes for catalyzing the reaction.

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In the first step of B-Oxidation, R Η Η Ο B HH -S-COA Acyl COA In the third step of B-Oxidation, ОНН О T || R-C-C-C -S-COA Acyl COA dehydrogenase L-B-Hydroxyacyl CoA R- B-Hydroxyacyl CoA dehydrogenase H H Η Ο R- trans-Enoyl COA is the oxidizing agent. -S-COA is the oxidizing agent. || -CH₂-C S-CoA B-Ketoacyl COA
Fatty acids and triglycerides are an important source of nutrition and a dense form of stored energy. Digestion of fats yields more energy per gram than digestion of carbohydrates. Each turn on the B-oxidation spiral results in the formation of a new acetyl COA molecule. This molecule can then be used to generate more energy in A) fatty acid synthesis B) ketolysis C) glycolysis D) tricarboxylic acid cycle E) oxidative phosphorylation
Most fatty acids have an even number of carbons and, therefore, are completely metabolized to acetyl-CoA. A fatty acid with an odd number of carbons is metabolized to acetyl-CoA and one equivalent of propionyl-CoA. The following two reactions convert propionyl-CoA into succinyl-CoA, a citric acid cycle intermediate, so it can be further metabolized. Each of the reactions requires a coenzyme. Identify the coenzyme for each step. From what vitamins are the coenzymes derived?

Chapter 24 Solutions

Organic Chemistry, Books a la Carte Edition (8th Edition)

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