NESTER'S MICROBIOLOGY
9th Edition
ISBN: 9781264826940
Author: Anderson
Publisher: MCG
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Chapter 24, Problem 3SA
Summary Introduction
To review:
The working of Helicobacter pylori in causing stomach ulcers.
Introduction:
Helicobacter pylori is a Gram-negative and microaerophilic bacteria, which is found usually in the stomach of the individual. It causes chronic gastritis and ulcers in the stomach. The researchers have developed a link between this bacteria and duodenal ulcers and stomach cancer.
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19. On the diagram below
a. Label the three pictures as: DNA; polypeptide; or RNA.
b. Label the arrows as: translation or transcription/RNA processing.
c. Add the following details to the diagram.
Promoter region
TATA box
Transcription start site
Transcription terminator
Intron (A,B,C,D)
Exons (1,2,3,4,5)
Splice sites
5' cap
5' UTR (untranslated region)
3' poly A tail
3' UTR (untranslated region)
Translational start (AUG)
Translational stop (UGA, UAG, or UAA)
N and C ends of polypeptide
0000
Match the letter labels in the figure below to the terms. Some letter
labels are not used.
MNNNNNNIN
M
C
B
A
M
D
F
E
H
K
G
8
The diagram below illustrates a quorum sensing pathway from Staphylococcus aureus. Please answer the following questions.
1. Autoinduction is part of the quorum sensing system. Which promoter (P2 or P3) is critical for autoinduction?
2)This staphylococcus aureus grows on human wounds, causing severe infections. You would like to start a clinical trial to treat these wound infections. Please describe:
a) What molecule do you recommend for the trial. Why?
b) Your trial requires that Staphylococcus aureus be isolated from the wound and submitted to genome sequencing before admittance. Why? What are you testing for?
3) If a mutation arises where the Promoter P3 is constitutively active, how would that influence sensitivity to AIP? Please explain your rationale.
4) This pathway is sensitive to bacterial cell density. Describe two separate mutation that would render the pathway active independent of cell density. Briefly explain your rationale.
Mutation 1
Mutation 2
Chapter 24 Solutions
NESTER'S MICROBIOLOGY
Ch. 24 -
1. Describe two characteristics of Streptococcus...Ch. 24 - Describe the process of periodontal disease.Ch. 24 - Prob. 3SACh. 24 - Prob. 4SACh. 24 - Prob. 5SACh. 24 - How do Shigella cells move from one host cell to...Ch. 24 - Name four different pathogenic groups of...Ch. 24 -
8. What predisposes someone to a Clostridium...Ch. 24 - Prob. 9SACh. 24 -
10. Contrast the cause and epidemiology of...
Ch. 24 - Which of the following about intestinal bacteria...Ch. 24 - Prob. 2MCCh. 24 - Prob. 3MCCh. 24 - Vibrio cholerae pathogenesis involves all of the...Ch. 24 - Prob. 5MCCh. 24 - Prob. 6MCCh. 24 - Prob. 7MCCh. 24 - Prob. 8MCCh. 24 - Prob. 9MCCh. 24 - Prob. 10MCCh. 24 - Prob. 1ACh. 24 - Prob. 2ACh. 24 - Prob. 1CTCh. 24 - Prob. 2CT
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