FUNDAMENTALS OF BIOCHEMISTRY - LL FD
FUNDAMENTALS OF BIOCHEMISTRY - LL FD
5th Edition
ISBN: 9781119598022
Author: Voet
Publisher: WILEY
bartleby

Concept explainers

bartleby

Videos

Question
Book Icon
Chapter 24, Problem 35CQ
Summary Introduction

To calculate: The linking number (L), writhing number (W), and the twist of both constrained and unconstrained conformational states of the given DNA circle.

Concept introduction: DNA molecules have different conformational changes based upon its state that could be described by the topological characteristics of the DNA. Topological characteristics of a particular DNA consist of three important parameters. Those include- Linking number, twist, and writhing. Twist number (T) is the total number of turns in the helix of the circular DNA and writhing (W) depicts the shape of the whole DNA molecule. The algebraic sum of both the twist number and writhing gives the linking number (L).

Summary Introduction

To calculate: The superhelix density of both the constrained and unconstrained DNA.

Concept introduction: DNA molecules have different conformational changes based upon its state that could be described by the topological characteristics of the DNA. Topological characteristics of a particular DNA consist of three important parameters. Those include- Linking number, twist, and writhing.

Twist number (T) is the total number of turns in the helix of the circular DNA and writhing (W) depicts the shape of the whole DNA molecule. The algebraic sum of both the twist number and writhing gives the linking number (L). Superhelical density or superhelix density (σ) is the expression that is used to symbolize the level of supercoiling in a DNA molecule is represented by the between number of turns added or removed to the number of turns in relaxed state.

Blurred answer
Students have asked these similar questions
The rate data from an enzyme catalyzed reaction with and without an inhibitor present is found in the image.  Question: what is the KM  and Vm and the nature of inhibition
1. Estimate the concentration of an enzyme within a living cell. Assume that:  (a): fresh tissue is 80% water and all of it is intracellular (b): the total soluble protein represents 15% of the weight (c): all the soluble proteins are enzymes (d): the average molecular weight of the proteins is 150,000 (E): about 100 different enzymes are present   please help I am lost
Please help
Knowledge Booster
Background pattern image
Biochemistry
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biochemistry and related others by exploring similar questions and additional content below.
Similar questions
SEE MORE QUESTIONS
Recommended textbooks for you
Text book image
Biochemistry
Biochemistry
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:W. H. Freeman
Text book image
Lehninger Principles of Biochemistry
Biochemistry
ISBN:9781464126116
Author:David L. Nelson, Michael M. Cox
Publisher:W. H. Freeman
Text book image
Fundamentals of Biochemistry: Life at the Molecul...
Biochemistry
ISBN:9781118918401
Author:Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher:WILEY
Text book image
Biochemistry
Biochemistry
ISBN:9781305961135
Author:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher:Cengage Learning
Text book image
Biochemistry
Biochemistry
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Cengage Learning
Text book image
Fundamentals of General, Organic, and Biological ...
Biochemistry
ISBN:9780134015187
Author:John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. Peterson
Publisher:PEARSON
DNA vs RNA (Updated); Author: Amoeba Sisters;https://www.youtube.com/watch?v=JQByjprj_mA;License: Standard youtube license