Anatomy & Physiology (6th Edition)
6th Edition
ISBN: 9780134156415
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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Textbook Question
Chapter 24, Problem 2SAQ
Trace the pathway a creatinine molecule takes from a glomerulus to the urethra. Name every microscopic or gross structure it passes through on its journey.
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The presence of either protein or glucose in a urinalysis is abnormal, but these two molecules end up in the urine for different reasons. For each of these molecules, briefly describe where in the urine production process (i.e., glomerular filtration, tubular reabsorption or tubular secretion) the problem occurs, and why it might happen.
Now, consider a molecule of antibiotic that is secreted from the peritubular capillaries into the filtrate at the proximal tubule. Trace the pathway this antibiotic molecule would take from the renal artery to the point at which it exits the body of a female in the urine.
The process of hydrogen ion secretion in the proximal convoluted tubule occurs via which of the following mechanisms?
Choose from the following:
(A) hydrogen ions diffuse out of the glomerular filtrate of the proximal convoluted tubule, through extracellular fluid and into the peritubular blood
(B) carbon dioxide diffuses into the proximal convoluted tubule cell from peritubular capillary blood; undergoes a chemical reaction to form carbonic acid; dissociates into hydrogen and bicarbonate ions; the hydrogen ion diffuses into the glomerular filtrate of the proximal convoluted tubule
(C) hydrogen ions diffuse out of the peritubular capillary blood, through extracellular fluid and into the filtrate of the proximal convoluted tubule
(D) carbon dioxide diffuses into the proximal convoluted tubule cell from the glomerular filtrate; undergoes a chemical reacdtion to form carbonic acid; dissociates into hydrogen and bicarbonate ions; the hydrogen ions diffuse into the peritubular blood
Chapter 24 Solutions
Anatomy & Physiology (6th Edition)
Ch. 24.1 - Prob. 1CYUCh. 24.1 - From inside to outside, list the three layers of...Ch. 24.1 - The lumen of the ureter is continuous with a space...Ch. 24.2 - Name the tubular components of a nephron in the...Ch. 24.2 - What are the structural differences between...Ch. 24.2 - What type of capillaries are the glomerular...Ch. 24.2 - Prob. 19CYUCh. 24.3 - In the kidneys, tubular secretion of a substance...Ch. 24.4 - Extrinsic and intrinsic controls of GFR serve two...Ch. 24.4 - Calculate net filtration pressure given the...
Ch. 24.4 - Which of the pressures that determine NFP is...Ch. 24.5 - In which part of the nephron does most...Ch. 24.5 - How does the movement of Na+ drive the...Ch. 24.5 - MAKING conections Primary and secondary active...Ch. 24.6 - List several substances that are secreted into the...Ch. 24.7 - Describe the special characteristics of the...Ch. 24.7 - Under what conditions is ADH released from the...Ch. 24.8 - What would you expect the normal clearance value...Ch. 24.8 - What are the three major nitrogenous wastes...Ch. 24.9 - A kidney stone blocking a ureter would interfere...Ch. 24.9 - What is the trigone of the bladder, and which...Ch. 24.9 - Name the three regions of the male urethra.Ch. 24.9 - How does the detrusor respond to increased firing...Ch. 24.9 - MAKING connections Compare the structure and...Ch. 24 - The lowest blood concentration of nitrogenous...Ch. 24 - The glomerular capillaries differ from other...Ch. 24 - Damage to the renal medulla would interfere first...Ch. 24 - Which is reabsorbed by the proximal convoluted...Ch. 24 - Glucose is not normally found in the urine because...Ch. 24 - Filtration at the glomerulus is inversely related...Ch. 24 - Tubular reabsorption (a) of glucose and many other...Ch. 24 - If a freshly voided urine sample contains...Ch. 24 - Conditions such as diabetes mellitus and...Ch. 24 - Which of the following is/are true about ADH? (a)...Ch. 24 - What is the importance of the perirenal fat...Ch. 24 - Trace the pathway a creatinine molecule takes from...Ch. 24 - Explain the important differences between blood...Ch. 24 - Describe the mechanisms that contribute to renal...Ch. 24 - Prob. 5SAQCh. 24 - Describe what is involved in active and passive...Ch. 24 - Explain how the peritubular capillaries are...Ch. 24 - Explain the process and purpose of tubular...Ch. 24 - How does aldosterone modify the chemical...Ch. 24 - Explain why the filtrate becomes hypotonic as it...Ch. 24 - How does urinary bladder anatomy support its...Ch. 24 - Define micturition and describe the micturition...Ch. 24 - Lets return to Kyle Boulard, whom we met in the...Ch. 24 - Lets return to Kyle Boulard, whom we met in the...Ch. 24 - Lets return to Kyle Boulard, whom we met in the...Ch. 24 - Lets return to Kyle Boulard, whom we met in the...Ch. 24 - Lets return to Kyle Boulard, whom we met in the...Ch. 24 - Lets return to Kyle Boulard, whom we met in the...Ch. 24 - Lets return to Kyle Boulard, whom we met in the...
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- The epithelium lining of the proximal convoluted tubule has a brush border. Name the cell structure that forms the brush border and state its function.arrow_forwardWhich of the following pathways best describe the structures which urine has to flow through before being excreted out of the body? (Hint: some structures may be omitted, so just make sure the general order is correct) 1-Collecting duct -> bladder -> ureter 2-Collecting duct -> ureter -> bladder -> urethra 3-Collecting duct -> urethra -> bladder -> ureter 4-Major calyx -> minor calyx -> renal pelvis -> urethraarrow_forwardFred was diagnosed 6 months ago with liver cancer. His liver is no longer able to make the necessary amount of proteins needed by the body. What effect, if any, would this have on the net glomerular filtration rate? (Hint, decide which of the 3 forces contributing to the net filtration rate is affected. Then adjust numbers in the equation to determine if there is an increase, decrease, or no change to the net filtration rate). Group of answer choices A) Blood colloid osmotic pressure would be decreased, increasing the net glomerular filtration rate. B) Blood colloid osmotic pressure would be decreased, decreasing the net glomerular filtration rate. C) Capsular hydrostatic pressure would be decreased, increasing the net glomerular filtration rate. D) Capsular hydrostatic pressure would be decreased, decreasing the net glomerular filtration rate. E) There would be no effect on the net glomerular filtration rate.arrow_forward
- The opening indicated by the black arrow indicates a 'fenestra' or pore within the glomerular capillary endothelium. Which of the following is the approximate size of the largest molecule allowed to pass through this opening? Choose from the following: (A) 5 - 6 nm (B) 50 - 70 nm (C) 200 - 300 nm (D) 700 - 800 nmarrow_forwardTrace the path taken by the renal filtrate (and urine) from the glomerulus to the urethra. Name every microscopic and gross tube and structure that it passes through on its journey.arrow_forwardWhich of the following does not contribute to the process of filtration? (a) active transport by epithelial cells lining renal tubules (b) large surface area for filtration (c) low permeability of glomerular capillaries (d) high hydrostatic blood pressure in glomerular capillaries (e) podocytesarrow_forward
- The structures marked by the white asterisk are identified as which of the following? Choose from the following: (A) thin segments of the nephron loop (B) vasa recta (C) glomerular capillaries (D) cortical peritubular capillariesarrow_forwardTrace the pathway of a metabolic waste from glomerulus to urethra. Be certain to state anatomical landmarks and physiological actions during the route.arrow_forwardDraw a schematic diagram showing the flow of water and salts in the proximal tubule of the kidney. In this diagram, put the lumen on the left side of the diagram and the extracellular fluids on the right side of the diagram. Indicate where the lumen is, where the extracellular fluid is, where the apical portion of the cell is, and show the location of the proteins that are responsible for the movement of water and salts and glucose reabsorption in this area of the kidneyarrow_forward
- Identify all of the following that are functions of the kidney: (a) maintain blood pH; (b) regulate blood ion concentrations; (c) regulate blood volume and blood pressure; (d) eliminate wastes, some hormones, and certain drugs from the blood; (e) release renin; (f) release erythropoietin; and (g) stimulate the final step in calcitriol formation.arrow_forwardName and define the process that occurs in glomerulus.arrow_forwardThe renal handling of a novel drug is being studied. When the drug is present in the blood, it is filtered into the Bowman’s capsule and secreted via transport proteins in the renal tubules, but it is NOT reabsorbed. The lines on the following graph represent filtration, secretion and excretion rates of this drug at various plasma concentrations. For the three lines shown (labeled A-C) identify which line represents filtration, which line represents secretion, and which line represents excretion Explain how you determined this.arrow_forward
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