Explanation The three main physiological processes of the kidney—glomerular filtration, tubular reabsorption, and tubular secretion—lead to the removal of metabolic wastes from the body in the form of urine. The rate at which filtrate is formed by both kidneys is called GFR (glomerular filtration rate). The normal value of GFR is 125 mL/minute and there are several (neural, endocrine and renal) mechanisms that help maintain the normal value of GFR. The value of GFR is 35 mL/min in Mr. Wu, as determined after inulin administration. It shows that the kidneys are not able to work properly, exhibiting a condition called renal failure...

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Question

Chapter 24, Problem 2AYKA

Summary Introduction

Case summary:

The GFR of a patient with a kidney disease is found to be approximately 35 mL/min. The medication taken by him gets excreted from the body, under normal conditions. However, his plasma contains a higher than normal concentration of the medication.

Characters in the case:

Mr. Wu, who is suffering from the kidney disease.

Adequate information:

The GFR of the patient (as estimated value, obtained through inulin administration) was found to be 35 mL/min, which is significantly lower than the normal value of 125 mL/min (milliliter per minute).

To determine:

The health of his kidneys. Also, the relation between the decreased GFR and the high level of medication in his plasma.

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Chapter 24, Problem 1AYKA

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Chapter 24 Solutions

HUMAN ANA.+PHYS.W/LAB MANUAL >BCI<

Ch. 24.1 - What are the organs of the urinary system?Ch. 24.1 - 2. What are the basic functions of the kidneys? Ch. 24.2 - Prob. 1QC Ch. 24.2 - 2. What are the three regions of the kidney, and...Ch. 24.2 - Prob. 3QC Ch. 24.2 - Trace the sequence of blood flow through the...Ch. 24.2 - Prob. 5QC Ch. 24.2 - Prob. 6QC Ch. 24.2 - Trace the pathway filtrate takes through the...Ch. 24.3 - Prob. 1QC

Ch. 24.3 - 2. How do tubular reabsorption and tubular...Ch. 24.4 - Prob. 1QC Ch. 24.4 - Prob. 2QC Ch. 24.4 - Prob. 3QC Ch. 24.4 - 4. What is the GFR? Ch. 24.4 - Prob. 5QC Ch. 24.4 - Prob. 6QC Ch. 24.4 - 7. How does tubuloglomerular feedback affect the...Ch. 24.4 - Prob. 8QC Ch. 24.4 - Prob. 9QC Ch. 24.4 - Prob. 10QC Ch. 24.4 - How does the sympathetic nervous system affect the...Ch. 24.5 - Prob. 1QC Ch. 24.5 - 2. What are the three types of transport...Ch. 24.5 - Prob. 3QC Ch. 24.5 - What is obligatory water reabsorption?Ch. 24.5 - How do the permeabilities of the two limbs of the...Ch. 24.5 - Prob. 6QC Ch. 24.5 - Prob. 7QC Ch. 24.5 - Prob. 8QC Ch. 24.6 - Prob. 1QC Ch. 24.6 - Prob. 2QC Ch. 24.6 - Prob. 3QC Ch. 24.6 - Prob. 4QC Ch. 24.6 - 5. What three factors allow the kidney to produce...Ch. 24.6 - 6. How is concentrated urine produced? Ch. 24.8 - 1. What is the normal composition of urine? Ch. 24.8 - Prob. 2QC Ch. 24.8 - 3. What is renal clearance, and what is it used...Ch. 24.9 - Prob. 1QC Ch. 24.9 - 2. What are the functions of the ureters and...Ch. 24.9 - Prob. 3QC Ch. 24.9 - Prob. 4QC Ch. 24.9 - Prob. 5QC Ch. 24 - What are the four main organs of the urinary...Ch. 24 - 2. Which of the following is not a physiological...Ch. 24 - Mark the following statements as true or false. If...Ch. 24 - Prob. 4CYR Ch. 24 - Prob. 5CYR Ch. 24 - Which of the following substances would pass...Ch. 24 - Mark the following statements as true or false. If...Ch. 24 - Fill in the blanks for the following statements:...Ch. 24 - Which of the following is false about the GFR? a....Ch. 24 - The route by which substances are reabsorbed by...Ch. 24 - 11. Fill in the blanks: Glomerular hydrostatic...Ch. 24 - Dilute urine is produced when decreased levels of...Ch. 24 - Prob. 13CYR Ch. 24 - Prob. 14CYR Ch. 24 - Prob. 15CYR Ch. 24 - 16. The GFR may be estimated by measuring the rate...Ch. 24 - Prob. 17CYR Ch. 24 - Prob. 1CYU Ch. 24 - Prob. 2CYU Ch. 24 - Prob. 3CYU Ch. 24 - Why must the kidneys establish a concentration...Ch. 24 - 1. Drugs that treat hypertension, or high blood...Ch. 24 - Prob. 2AYKA Ch. 24 - 3. Deana is a 4-year-old girl with a rare genetic...Ch. 24 - 4. Explain how each of the drugs in question 1...Ch. 24 - 5. What might it mean if you found a high...

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Solution Summary: The author analyzes the relationship between the decreased GFR and the high level of medication in the patient's plasma.

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