The synthesis of compound 1 has to be shown from alkenes 2 and 3. Concept Introduction: Simmons–Smith reaction: It involves reaction of alkenes with organozinc reagent namely ICH 2 ZnI which results in formation of three–membered ring in product. This is a concerted reaction in which the configuration of starting alkene is preserved. Swern oxidation: Primary and secondary alcohols undergoes oxidation reaction using dimethyl sulfoxide, oxalyl chloride and triethyl amine which provides aldehyde and ketones . Wittig Reaction: It is an organic reaction where an aldehyde or a ketone gets converted to an alkene by replacing carbonyl group by a C=C bond. A phosphorous ylide is used for this conversion. It is a neutral molecule where a positively charged phosphorous is attached to a negatively charged carbon atom. Grubbs catalyst: This catalyst is used to achieve alkene metathesis. It contain transition metal namely Ru which is doubly bonded with carbon atom. Dienes in presence of Grubbs catalyst, alkene metathesis serve as method of ring formation.

Question

Want to see the full answer?

Answer 1

Question

Chapter 23, Problem 62IP

Interpretation Introduction

Interpretation:

The synthesis of compound 1 has to be shown from alkenes 2 and 3.

Concept Introduction:

Simmons–Smith reaction: It involves reaction of alkenes with organozinc reagent namely ICH2ZnI which results in formation of three–membered ring in product. This is a concerted reaction in which the configuration of starting alkene is preserved.

Swern oxidation: Primary and secondary alcohols undergoes oxidation reaction using dimethyl sulfoxide, oxalyl chloride and triethyl amine which provides aldehyde and ketones.

Wittig Reaction:

It is an organic reaction where an aldehyde or a ketone gets converted to an alkene by replacing carbonyl group by a C=C bond. A phosphorous ylide is used for this conversion. It is a neutral molecule where a positively charged phosphorous is attached to a negatively charged carbon atom.

Grubbs catalyst: This catalyst is used to achieve alkene metathesis. It contain transition metal namely Ru which is doubly bonded with carbon atom.

Dienes in presence of Grubbs catalyst, alkene metathesis serve as method of ring formation.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

Predict the major products of this organic reaction: 1. LIAIHA 2. H₂O ? Note: be sure you use dash and wedge bonds when necessary, for example to distinguish between major products with different stereochemistry. Click and drag to start drawing a structure. X : ☐

For each reaction below, decide if the first stable organic product that forms in solution will create a new C - C bond, and check the appropriate box. Next, for each reaction to which you answered "Yes" to in the table, draw this product in the drawing area below. Note for advanced students: for this problem, don't worry if you think this product will continue to react under the current conditions - just focus on the first stable product you expect to form in solution. NH2 tu ? ? OH Will the first product that forms in this reaction create a new CC bond? Yes No Will the first product that forms in this reaction create a new CC bond? Yes No C $ ©

As the lead product manager at OrganometALEKS Industries, you are trying to decide if the following reaction will make a molecule with a new C-C bond as its major product: 1. MgCl ? 2. H₂O* If this reaction will work, draw the major organic product or products you would expect in the drawing area below. If there's more than one major product, you can draw them in any arrangement you like. Be sure you use wedge and dash bonds if necessary, for example to distinguish between major products with different stereochemistry. If the major products of this reaction won't have a new CC bond, just check the box under the drawing area and leave it blank. Click and drag to start drawing a structure. This reaction will not make a product with a new CC bond. G m