INTEG. PRIN OF ZOO >LL< W/ CONNECT - FD
18th Edition
ISBN: 9781265230234
Author: HICKMAN
Publisher: MCG
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Textbook Question
Chapter 23, Problem 1RQ
What characteristics shared by the three deuterostome phyla indicate a monophyletic group of interrelated animals?
Expert Solution & Answer
Summary Introduction
To determine: The three characteristics shared by the deuterostomes that indicate a monophyletic group of interrelated animals.
Introduction: Embryonic development is an intricate process where a large number of genes, proteins, enzymes, and signaling methods are required to accurately form the different structures of the growing fetus.
Explanation of Solution
The three characteristics that are shared by deuterostomes that indicate the monophyletic group of interrelated animals are as follows:
- The deuterostomes and the chordates have radial cleavage.
- In the case of deuterostomes, the anus is derived from the first embryonic opening and the mouth is derived from the second embryonic opening.
- The coelom is formed by the fusion of the enterocoelous pouches.
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Digoxin: Intravenous Bolus - Two Compartment Model
Drug
Digoxin
Route:
IV Bolus
Dose:
0.750 mg
Plasma Concentration Time Profile
Beta
Alpha
Time (hrs)
Conc (ng/ml)
LN
(ng/ml)
LN
(ng/ml)
LN
0.00
#NUM!
#NUM!
#NUM!
0.10
12.290
2.509
#NUM!
#NUMI
0.60
6.975
1.942
#NUM!
#NUMI
1.00
4.649
1.537
#NUM!
#NUMI
2.00
2.201
0.789
#NUM!
#NUM!
3.00
1.536
0.429
#NUM!
#NUM!
4.00
1.342
0.294
#NUM!
#NUM!
5.00
1.273
0.241
#NUM!
#NUMI
6.00
1.238
0.213
#NUM!
#NUM!
7.00
1.212
0.192
#NUM!
#NUM!
8.00
1.188
0.172
#NUMI
#NUM!
9.00
1.165
0.153
#NUM!
#NUMI
10.00
1.143
0.134
#NUMI
#NUM!
11.00
1.122
0.115
#NUM!
12.00
1.101
0.096
#NUMI
13.00
1.080
0.077
#NUMI
16.00
1.020
0.020
#NUMI
24.00
0.876
-0.132
#NUMI
Pharmacokinetic Parameters
Parameter
Value
Alpha
B
Beta
Units
ng/ml
hr-1
ng/ml
hr-1
CO
ng/ml
H.C
AUC
ng x hr/ml
Vc
Vbeta
Vss
C
L/hr
TK (alpha)
hr
TX (beta)
days
5+
F3
F4
F5
0+
F6
F7
%
6
95
14
#3
29
&
t
F8
F9
FW
EW
Linuron, a derivative of urea, is used as an herbicide. Linuron serum levels were measured in 4Kg
rabbits following a bolus IV injection of 10mg/kg.
Time (minutes)
Serum Linuron Levels (ug/ml)
following IV dose
10
15.48
20
8.60
30
5.90
45
3.78
60
2.42
90
1.49
120
0.93
180
0.60
240
0.41
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0.29
360
0.22
Analyze this data and perform the necessary calculations to determine the following pharmacokinetic
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Give the y axis (name and units, if any) of the terminal line:
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Give the x axis (name and units, if any) of the residual line:
Give the y axis (name and units, if any) of the residual line:
Chapter 23 Solutions
INTEG. PRIN OF ZOO >LL< W/ CONNECT - FD
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