Concept explainers
(a)
Interpretation:
The synthesis of
Concept introduction:
In

Answer to Problem 22.82AP
The synthesis of
Explanation of Solution
The reaction of
Figure 1
The synthesis of
(b)
Interpretation:
The synthesis of
Concept introduction:
In organic chemistry, the class of functional group which is derived from conjugated diene by replacing one double bond with a carbonyl group. The dienone compound is in conjugation to each other.

Answer to Problem 22.82AP
The synthesis of
Explanation of Solution
The reaction of
Figure 2
The synthesis of
(c)
Interpretation:
The synthesis of
Concept introduction:
An ester is a derivative of carboxylic which is obtained by replacing the

Answer to Problem 22.82AP
The synthesis of
Explanation of Solution
Diethyl heptanedioate in presence of
Figure 3
The synthesis of
(d)
Interpretation:
The synthesis of
Concept introduction:
An ester is a derivative of carboxylic which is obtained by replacing the

Answer to Problem 22.82AP
The synthesis of
Explanation of Solution
The reaction of diethyl malonate in presence of base and then
Figure 4
The synthesis of
(e)
Interpretation:
The synthesis of
Concept introduction:
An ester is a derivative of

Answer to Problem 22.82AP
The synthesis of
Explanation of Solution
The reaction of ethyl acrylate with ammonia forms amide derivative. It undergoes reduction reaction with
Figure 5
The synthesis of
(f)
Interpretation:
The synthesis of
Concept introduction:
In organic chemistry, the compound with the molecular formula

Answer to Problem 22.82AP
The synthesis of
Explanation of Solution
The reaction of acrylonitrile with
Figure 6
The synthesis of
(g)
Interpretation:
The synthesis of
Concept introduction:
Carboxylic acid is a class of organic compound contains a

Answer to Problem 22.82AP
The synthesis of
Explanation of Solution
Esterification of phenylacetic acid forms ethyl
Figure 7
The synthesis of
(h)
Interpretation:
The synthesis of
Concept introduction:
In Aldol condensation reaction, the base abstracts an acidic proton from the

Answer to Problem 22.82AP
The synthesis of
Explanation of Solution
The reaction of acetophenone in presence of base abstracts a
Figure 8
The synthesis of
(i)
Interpretation:
The synthesis of deuterium substituted diphenylethanol from phenylacetic acid is to be stated.
Concept introduction:
Carboxylic acid is a class of organic compound that contains a

Answer to Problem 22.82AP
The synthesis of di-deuterium substituted diphenyl ethanol from phenylacetic acid is shown below.
Explanation of Solution
Reaction of
Figure 9
The synthesis of deuterium substituted diphenyl ethanol from phenylacetic acid is shown in Figure 9.
(j)
Interpretation:
The synthesis of tetra-deuterium substituted product from cyclohexanone is to be stated.
Concept introduction:
In organic chemistry, the carbonyl compound is a class of functional group which contains a

Answer to Problem 22.82AP
The synthesis of tetra-deuterium substituted product from cyclohexanone is shown below.
Explanation of Solution
The reaction of cyclohexanone with
Figure 10
The synthesis of tetra-deuterium substituted from cyclohexanone is shown in Figure 10.
(k)
Interpretation:
The synthesis of
Concept introduction:
Friedel Craft acylation is an electrophilic aromatic substitution reaction. In this reaction, the synthesis of the monoacylated product takes place from the reaction between aromatic rings and acyl chlorides. The organic reaction in which an organohalide is reacted with alcohols or phenols to form ethers is Willamson synthesis reaction.

Answer to Problem 22.82AP
The synthesis of
Explanation of Solution
The reaction of phenol with methyl halide forms methylphenyl ether. It reacts with acetyl chloride followed by chlorination in sunlight. Then it reacts with phenol to give the desired product. The synthesis of
Figure 11
The synthesis of
(l)
Interpretation:
The synthesis of
Concept introduction:
An ester is a derivative of carboxylic which is obtained by replacing the

Answer to Problem 22.82AP
The synthesis of
Explanation of Solution
Methylation of diethyl malonate in the presence of sodium ethoxide and
Figure 12
The synthesis of
(m)
Interpretation:
The synthesis of
Concept introduction:
An ester is a derivative of carboxylic which is obtained by replacing the

Answer to Problem 22.82AP
The synthesis of
Explanation of Solution
The hydrolysis reaction of
Figure13
The synthesis of
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Chapter 22 Solutions
ORGANIC CHEMISTRY SAPLING ACCESS + ETEX
- PROBLEMS Q1) Label the following salts as either acidic, basic, or neutral a) Fe(NOx) c) AlBr b) NH.CH COO d) HCOON (1/2 mark each) e) Fes f) NaBr Q2) What is the pH of a 0.0750 M solution of sulphuric acid?arrow_forward8. Draw all the resonance forms for each of the fling molecules or ions, and indicate the major contributor in each case, or if they are equivalent (45) (2) -PH2 سمة مدarrow_forwardA J то گای ه +0 Also calculate the amount of starting materials chlorobenzaldehyde and p-chloroacetophenone required to prepare 400 mg of the given chalcone product 1, 3-bis(4-chlorophenyl)prop-2-en-1-one molar mass ok 1,3-bis(4-Chlorophenyl) prop-2-en-1-one = 277.1591m01 number of moles= 0.400/277.15 = 0.00144 moles 2 x 0.00 144=0.00288 moves arams of acetophenone = 0.00144 X 120.16 = 0.1739 0.1739x2=0.3469 grams of benzaldehyde = 0.00144X106.12=0.1539 0.1539x2 = 0.3069 Starting materials: 0.3469 Ox acetophenone, 0.3069 of benzaldehyde 3arrow_forward
- 1. Answer the questions about the following reaction: (a) Draw in the arrows that can be used make this reaction occur and draw in the product of substitution in this reaction. Be sure to include any relevant stereochemistry in the product structure. + SK F Br + (b) In which solvent would this reaction proceed the fastest (Circle one) Methanol Acetone (c) Imagine that you are working for a chemical company and it was your job to perform a similar reaction to the one above, with the exception of the S atom in this reaction being replaced by an O atom. During the reaction, you observe the formation of three separate molecules instead of the single molecule obtained above. What is the likeliest other products that are formed? Draw them in the box provided.arrow_forward3. For the reactions below, draw the arrows corresponding to the transformations and draw in the boxes the reactants or products as indicated. Note: Part A should have arrows drawn going from the reactants to the middle structure and the arrows on the middle structure that would yield the final structure. For part B, you will need to draw in the reactant before being able to draw the arrows corresponding to product formation. A. B. Rearrangement ΘΗarrow_forward2. Draw the arrows required to make the following reactions occur. Please ensure your arrows point from exactly where you want to exactly where you want. If it is unclear from where arrows start or where they end, only partial credit will be given. Note: You may need to draw in lone pairs before drawing the arrows. A. B. H-Br 人 C Θ CI H Cl Θ + Br Oarrow_forward
- 4. For the reactions below, draw the expected product. Be sure to indicate relevant stereochemistry or formal charges in the product structure. a) CI, H e b) H lux ligh Br 'Harrow_forwardArrange the solutions in order of increasing acidity. (Note that K (HF) = 6.8 x 10 and K (NH3) = 1.8 × 10-5) Rank solutions from least acidity to greatest acidity. To rank items as equivalent, overlap them. ▸ View Available Hint(s) Least acidity NH&F NaBr NaOH NH,Br NaCIO Reset Greatest acidityarrow_forward1. Consider the following molecular-level diagrams of a titration. O-HA molecule -Aion °° о ° (a) о (b) (c) (d) a. Which diagram best illustrates the microscopic representation for the EQUIVALENCE POINT in a titration of a weak acid (HA) with sodium. hydroxide? (e)arrow_forward
- Answers to the remaining 6 questions will be hand-drawn on paper and submitted as a single file upload below: Review of this week's reaction: H₂NCN (cyanamide) + CH3NHCH2COOH (sarcosine) + NaCl, NH4OH, H₂O ---> H₂NC(=NH)N(CH3)CH2COOH (creatine) Q7. Draw by hand the reaction of creatine synthesis listed above using line structures without showing the Cs and some of the Hs, but include the lone pairs of electrons wherever they apply. (4 pts) Q8. Considering the Zwitterion form of an amino acid, draw the Zwitterion form of Creatine. (2 pts) Q9. Explain with drawing why the C-N bond shown in creatine structure below can or cannot rotate. (3 pts) NH2(C=NH)-N(CH)CH2COOH This bond Q10. Draw two tautomers of creatine using line structures. (Note: this question is valid because problem Q9 is valid). (4 pts) Q11. Mechanism. After seeing and understanding the mechanism of creatine synthesis, students should be ready to understand the first half of one of the Grignard reactions presented in a past…arrow_forwardPropose a synthesis pathway for the following transformations. b) c) d)arrow_forwardThe rate coefficient of the gas-phase reaction 2 NO2 + O3 → N2O5 + O2 is 2.0x104 mol–1 dm3 s–1 at 300 K. Indicate whether the order of the reaction is 0, 1, or 2.arrow_forward
- Organic ChemistryChemistryISBN:9781305580350Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. FootePublisher:Cengage Learning

