The addition of Grignard reagent to an ester or a nitrile to synthesize 4 -phenylheptan- 4 -ol is to be explained. Concept introduction: The grignard reagent is used to generate R − carbanion which attacks on electron deficient center. Carbonyl group that has good leaving group gives substituted products. This reagent is used to convert the carbonyl group into alcohol.

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Answer 1

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Definition Definition Organic compounds that have a carbonyl group, C = O, as their functional group. The carbonyl group in ketones is placed somewhere in the middle of the molecular structure, which means, the C=O is attached to two alkyl groups or benzene rings. Just like all other homologous series, the naming of ketones is done using a common suffix “-one”. The general molecular formula is C n H 2n O. Functional group of a ketone

Chapter 21.9, Problem 21.28P

(a)

Interpretation Introduction

Interpretation:

The addition of Grignard reagent to an ester or a nitrile to synthesize 4-phenylheptan-4-ol is to be explained.

Concept introduction:

The grignard reagent is used to generate R− carbanion which attacks on electron deficient center. Carbonyl group that has good leaving group gives substituted products. This reagent is used to convert the carbonyl group into alcohol.

(b)

Interpretation Introduction

Interpretation:

The addition of Grignard reagent to an ester or a nitrile to synthesize heptan-4-ol is to be explained.

Concept introduction:

The grignard reagent is used to generate R− carbanion which attacks on electron deficient center. Carbonyl group that has good leaving group gives substituted products. This reagent is used to convert the carbonyl group into alcohol.

(c)

Interpretation Introduction

Interpretation:

The addition of Grignard reagent to an ester or a nitrile to synthesize pentan-2-one is to be explained.

Concept introduction:

The grignard reagent is used to generate R− carbanion which attacks electron deficient center. Carbonyl group that has good leaving group gives substituted products. This reagent is used to convert the nitrile group into ketone group.

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Stuc X ctclix ALE X A ALE אן A ALEX Lab (195 X Nut x M Inb x NU X NUT X Unt x + → C www-awu.aleks.com/alekscgi/x/Isl.exe/10_u-lgNslkr7j8P3jH-IQ1g8NUi-mObKa_ZLx2twjEhK7mVG6PulJI006NcKTV37JxMpZuyrVCdQolLAKqp_7U3r1GUD3... New Chrome available: Naomi Question 26 of 39 (4 points) | Question Attempt: 1 of Unlimited Give the IUPAC name. 2,3-dimethylhexane Part: 1/2 Part 2 of 2 Draw the skeletal structure of a constitutional isomer of the alkane above that contains a different number of carbons in its longest chain. Skip Part Check Click and drag to start drawing a structure. 3 Finance headline Q Search mwa Harvard Intensifi... X Save For Later 00 dlo HB Submit Assignment 2025 McGraw Hill LLC. All Rights Reserved. Terms of Use | Privacy Center | Accessibility a 9:11 PM 4/22/2025

Predict the product of this organic reaction: + NH2 HO A P+ H2O Specifically, in the drawing area below draw the skeletal ("line") structure of P. If there is no reasonable possibility for P, check the No answer box under the drawing area. Click and drag to start drawing a structure. ✓

个 Stuc X ctclix ALE X A ALE × A ALE X Lab x (195 × Nut x M Inbx EF 目 → C www-awu.aleks.com/alekscgi/x/Isl.exe/10_u-IgNslkr7j8P3jH-IQ1g8NUi-mObKa_ZLx2twjEhK7mVG6PulJI006NcKTV37JxMpz Chapter 12 HW = Question 27 of 39 (5 points) | Question Attempt: 1 of Unlimited Part: 1/2 Part 2 of 2 Give the IUPAC name. Check 3 50°F Clear ©2025 McGraw Hill L Q Search webp a عالياك

Answer 2

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Definition Definition Organic compounds that have a carbonyl group, C = O, as their functional group. The carbonyl group in ketones is placed somewhere in the middle of the molecular structure, which means, the C=O is attached to two alkyl groups or benzene rings. Just like all other homologous series, the naming of ketones is done using a common suffix “-one”. The general molecular formula is C n H 2n O. Functional group of a ketone

Chapter 21.9, Problem 21.28P

(a)

Interpretation Introduction

Interpretation:

The addition of Grignard reagent to an ester or a nitrile to synthesize 4-phenylheptan-4-ol is to be explained.

Concept introduction:

The grignard reagent is used to generate R− carbanion which attacks on electron deficient center. Carbonyl group that has good leaving group gives substituted products. This reagent is used to convert the carbonyl group into alcohol.

(b)

Interpretation Introduction

Interpretation:

The addition of Grignard reagent to an ester or a nitrile to synthesize heptan-4-ol is to be explained.

Concept introduction:

The grignard reagent is used to generate R− carbanion which attacks on electron deficient center. Carbonyl group that has good leaving group gives substituted products. This reagent is used to convert the carbonyl group into alcohol.

(c)

Interpretation Introduction

Interpretation:

The addition of Grignard reagent to an ester or a nitrile to synthesize pentan-2-one is to be explained.

Concept introduction:

The grignard reagent is used to generate R− carbanion which attacks electron deficient center. Carbonyl group that has good leaving group gives substituted products. This reagent is used to convert the nitrile group into ketone group.

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Answer 3

Question

Definition Definition Organic compounds that have a carbonyl group, C = O, as their functional group. The carbonyl group in ketones is placed somewhere in the middle of the molecular structure, which means, the C=O is attached to two alkyl groups or benzene rings. Just like all other homologous series, the naming of ketones is done using a common suffix “-one”. The general molecular formula is C n H 2n O. Functional group of a ketone

Chapter 21.9, Problem 21.28P

(a)

Interpretation Introduction

Interpretation:

The addition of Grignard reagent to an ester or a nitrile to synthesize 4-phenylheptan-4-ol is to be explained.

Concept introduction:

The grignard reagent is used to generate R− carbanion which attacks on electron deficient center. Carbonyl group that has good leaving group gives substituted products. This reagent is used to convert the carbonyl group into alcohol.

(b)

Interpretation Introduction

Interpretation:

The addition of Grignard reagent to an ester or a nitrile to synthesize heptan-4-ol is to be explained.

Concept introduction:

The grignard reagent is used to generate R− carbanion which attacks on electron deficient center. Carbonyl group that has good leaving group gives substituted products. This reagent is used to convert the carbonyl group into alcohol.

(c)

Interpretation Introduction

Interpretation:

The addition of Grignard reagent to an ester or a nitrile to synthesize pentan-2-one is to be explained.

Concept introduction:

The grignard reagent is used to generate R− carbanion which attacks electron deficient center. Carbonyl group that has good leaving group gives substituted products. This reagent is used to convert the nitrile group into ketone group.

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Answer 4

Question

Definition Definition Organic compounds that have a carbonyl group, C = O, as their functional group. The carbonyl group in ketones is placed somewhere in the middle of the molecular structure, which means, the C=O is attached to two alkyl groups or benzene rings. Just like all other homologous series, the naming of ketones is done using a common suffix “-one”. The general molecular formula is C n H 2n O. Functional group of a ketone

Chapter 21.9, Problem 21.28P

(a)

Interpretation Introduction

Interpretation:

The addition of Grignard reagent to an ester or a nitrile to synthesize 4-phenylheptan-4-ol is to be explained.

Concept introduction:

The grignard reagent is used to generate R− carbanion which attacks on electron deficient center. Carbonyl group that has good leaving group gives substituted products. This reagent is used to convert the carbonyl group into alcohol.

(b)

Interpretation Introduction

Interpretation:

The addition of Grignard reagent to an ester or a nitrile to synthesize heptan-4-ol is to be explained.

Concept introduction:

The grignard reagent is used to generate R− carbanion which attacks on electron deficient center. Carbonyl group that has good leaving group gives substituted products. This reagent is used to convert the carbonyl group into alcohol.

(c)

Interpretation Introduction

Interpretation:

The addition of Grignard reagent to an ester or a nitrile to synthesize pentan-2-one is to be explained.

Concept introduction:

The grignard reagent is used to generate R− carbanion which attacks electron deficient center. Carbonyl group that has good leaving group gives substituted products. This reagent is used to convert the nitrile group into ketone group.

Expert Solution & Answer

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Answer 5

Chapter 21.9, Problem 21.28P

(a)

Interpretation Introduction

Interpretation:

The addition of Grignard reagent to an ester or a nitrile to synthesize 4-phenylheptan-4-ol is to be explained.

Concept introduction:

The grignard reagent is used to generate R− carbanion which attacks on electron deficient center. Carbonyl group that has good leaving group gives substituted products. This reagent is used to convert the carbonyl group into alcohol.

(b)

Interpretation Introduction

Interpretation:

The addition of Grignard reagent to an ester or a nitrile to synthesize heptan-4-ol is to be explained.

Concept introduction:

The grignard reagent is used to generate R− carbanion which attacks on electron deficient center. Carbonyl group that has good leaving group gives substituted products. This reagent is used to convert the carbonyl group into alcohol.

(c)

Interpretation Introduction

Interpretation:

The addition of Grignard reagent to an ester or a nitrile to synthesize pentan-2-one is to be explained.

Concept introduction:

The grignard reagent is used to generate R− carbanion which attacks electron deficient center. Carbonyl group that has good leaving group gives substituted products. This reagent is used to convert the nitrile group into ketone group.

Answer 6

Chapter 21.9, Problem 21.28P

(a)

Interpretation Introduction

Interpretation:

The addition of Grignard reagent to an ester or a nitrile to synthesize 4-phenylheptan-4-ol is to be explained.

Concept introduction:

The grignard reagent is used to generate R− carbanion which attacks on electron deficient center. Carbonyl group that has good leaving group gives substituted products. This reagent is used to convert the carbonyl group into alcohol.

Answer 7

Chapter 21.9, Problem 21.28P

(a)

Interpretation Introduction

Interpretation:

The addition of Grignard reagent to an ester or a nitrile to synthesize 4-phenylheptan-4-ol is to be explained.

Concept introduction:

The grignard reagent is used to generate R− carbanion which attacks on electron deficient center. Carbonyl group that has good leaving group gives substituted products. This reagent is used to convert the carbonyl group into alcohol.

Answer 8

(b)

Interpretation Introduction

Interpretation:

The addition of Grignard reagent to an ester or a nitrile to synthesize heptan-4-ol is to be explained.

Concept introduction:

The grignard reagent is used to generate R− carbanion which attacks on electron deficient center. Carbonyl group that has good leaving group gives substituted products. This reagent is used to convert the carbonyl group into alcohol.

Answer 9

(b)

Interpretation Introduction

Interpretation:

The addition of Grignard reagent to an ester or a nitrile to synthesize heptan-4-ol is to be explained.

Concept introduction:

The grignard reagent is used to generate R− carbanion which attacks on electron deficient center. Carbonyl group that has good leaving group gives substituted products. This reagent is used to convert the carbonyl group into alcohol.

Answer 10

(c)

Interpretation Introduction

Interpretation:

The addition of Grignard reagent to an ester or a nitrile to synthesize pentan-2-one is to be explained.

Concept introduction:

The grignard reagent is used to generate R− carbanion which attacks electron deficient center. Carbonyl group that has good leaving group gives substituted products. This reagent is used to convert the nitrile group into ketone group.

Answer 11

(c)

Interpretation Introduction

Interpretation:

The addition of Grignard reagent to an ester or a nitrile to synthesize pentan-2-one is to be explained.

Concept introduction:

The grignard reagent is used to generate R− carbanion which attacks electron deficient center. Carbonyl group that has good leaving group gives substituted products. This reagent is used to convert the nitrile group into ketone group.

Answer 12

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Answer 13

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Answer 14

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Answer 15

Ch. 21.2F - Name the following carboxylic acid derivatives,...Ch. 21.4A - Prob. 21.2P Ch. 21.4A - Prob. 21.3P Ch. 21.4A - Prob. 21.4P Ch. 21.5C - Prob. 21.7P Ch. 21.6 - When ethyl 4-hydroxybutyrate is heated in the...Ch. 21.6 - Propose a mechanism for the following ring-opening...Ch. 21.6 - Prob. 21.15P Ch. 21.7B - Prob. 21.16P Ch. 21.7C - Prob. 21.19P

Solution Summary: The author explains the mechanism of the addition of Grignard reagent to an ester or a nitrile to synthesize heptan- 4 -ol.

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