Chapter 21.8, Problem 17P

Interpretation Introduction

(a)

Interpretation: The product obtained by the treatment of given compound with LDA, followed by ${\text{CH}}_{\text{3}}\text{I}$ is to be predicted.

Concept introduction: Alkylation of aldehydes and ketones takes place in the presence of a strong base. The use of appropriate base, solvent and temperature can yield one major product regioselectively.

Interpretation Introduction

(b)

Interpretation: The product obtained by the treatment of given compound with LDA, followed by ${\text{CH}}_{\text{3}}{\text{CH}}_{\text{2}}\text{I}$ is to be predicted.

Concept introduction: Alkylation of aldehydes and ketones takes place in the presence of a strong base. The use of appropriate base, solvent and temperature can yield one major product regioselectively.

Interpretation Introduction

(c)

Interpretation: The product obtained by the treatment of given compound with LDA, followed by ${\text{CH}}_{\text{3}}{\text{CH}}_{\text{2}}\text{I}$ is to be predicted.

Concept introduction: Alkylation of aldehydes and ketones takes place in the presence of a strong base. The use of appropriate base, solvent and temperature can yield one major product regioselectively.