HUMAN BIOLOGY LAB SPRING 2023 CUSTOM
16th Edition
ISBN: 9781307853087
Author: Mader
Publisher: MCG
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Chapter 21.3, Problem 2CYP
Summary Introduction
To analyze:
The chances of having a child with cystic fibrosis for parents who are homozygous normal for it.
Introduction:
Cystic fibrosis is a genetic disorder i.e. it is can be passed on from the parents to the offspring. It is inherited in recessive manner which means that an individual should have two recessive alleles of the gene for being diagnosed with cystic fibrosis. Even if one of the allele is dominant, it will mask the effect of the recessive allele and the
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19. On the diagram below
a. Label the three pictures as: DNA; polypeptide; or RNA.
b. Label the arrows as: translation or transcription/RNA processing.
c. Add the following details to the diagram.
Promoter region
TATA box
Transcription start site
Transcription terminator
Intron (A,B,C,D)
Exons (1,2,3,4,5)
Splice sites
5' cap
5' UTR (untranslated region)
3' poly A tail
3' UTR (untranslated region)
Translational start (AUG)
Translational stop (UGA, UAG, or UAA)
N and C ends of polypeptide
0000
Match the letter labels in the figure below to the terms. Some letter
labels are not used.
MNNNNNNIN
M
C
B
A
M
D
F
E
H
K
G
8
The diagram below illustrates a quorum sensing pathway from Staphylococcus aureus. Please answer the following questions.
1. Autoinduction is part of the quorum sensing system. Which promoter (P2 or P3) is critical for autoinduction?
2)This staphylococcus aureus grows on human wounds, causing severe infections. You would like to start a clinical trial to treat these wound infections. Please describe:
a) What molecule do you recommend for the trial. Why?
b) Your trial requires that Staphylococcus aureus be isolated from the wound and submitted to genome sequencing before admittance. Why? What are you testing for?
3) If a mutation arises where the Promoter P3 is constitutively active, how would that influence sensitivity to AIP? Please explain your rationale.
4) This pathway is sensitive to bacterial cell density. Describe two separate mutation that would render the pathway active independent of cell density. Briefly explain your rationale.
Mutation 1
Mutation 2
Chapter 21 Solutions
HUMAN BIOLOGY LAB SPRING 2023 CUSTOM
Ch. 21.1 - Distinguish between a genotype and a phenotype.Ch. 21.1 - Define allele, gene, dominant, and recessive as...Ch. 21.1 - Prob. 3LOCh. 21.1 - Define the following terms:Â gene, allele, locus,...Ch. 21.1 - Prob. 2CYPCh. 21.1 - Prob. 3CYPCh. 21.2 - Prob. 1LOCh. 21.2 - Calculate the probability of a specific genotype...Ch. 21.2 - Prob. 1CYPCh. 21.2 - Prob. 2CYP
Ch. 21.2 - Using a dihybrid cross as an example (see Fig....Ch. 21.3 - Interpret a human pedigree to identify the pattern...Ch. 21.3 - Prob. 2LOCh. 21.3 - Solve the following: In a pedigree, all the...Ch. 21.3 - Prob. 2CYPCh. 21.3 - Explain why some incidences of autosomal recessive...Ch. 21.4 - Prob. 1LOCh. 21.4 - Prob. 2LOCh. 21.4 - Prob. 3LOCh. 21.4 - Prob. 1BTSCh. 21.4 - Prob. 2BTSCh. 21.4 - Prob. 1CYPCh. 21.4 - Prob. 2CYPCh. 21.4 - Discuss the potential evolutionary advantages of...Ch. 21.5 - Prob. 1LOCh. 21.5 - Prob. 2LOCh. 21.5 - Prob. 1CYPCh. 21.5 - Prob. 2CYPCh. 21.5 - Discuss why X-linked disorders are more common...Ch. 21.5 - Prob. 1BTSCh. 21.5 - Prob. 2BTSCh. 21 - Prob. 1ACh. 21 - 2. Which of the toll awing terms refers to...Ch. 21 - Prob. 3ACh. 21 - Prob. 4ACh. 21 - 5. The genotype of an individual with the dominant...Ch. 21 - Prob. 6ACh. 21 - Prob. 7ACh. 21 - Prob. 8ACh. 21 - Which of the following disorders is caused by a...Ch. 21 - Prob. 10ACh. 21 - Prob. 11ACh. 21 - Prob. 12ACh. 21 - Which of the following terms may be used to...Ch. 21 - Prob. 14ACh. 21 - Prob. 15ACh. 21 - Prob. 1TCCh. 21 - Prob. 2TCCh. 21 - Prob. 3TC
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