Human Anatomy (8th Edition)
Human Anatomy (8th Edition)
8th Edition
ISBN: 9780134243818
Author: Elaine N. Marieb, Patricia Brady Wilhelm, Jon B. Mallatt
Publisher: PEARSON
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Chapter 21, Problem 3CRCAQ
Summary Introduction

To review:

The occurrence of splenomegaly by portal hypertension.

Introduction:

Portal hypertension is a condition where the portal venous system blood pressure is high. The blood vessels are categorized into arteries, veins, and capillaries. The arteries carry oxygen rich blood from the heart and transport it throughout the body whereas the veins receive deoxygenated blood from the body parts and transport it to the heart. Splenomegaly is a condition where the spleen becomes enlarged.

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Imagine that you are a clinical geneticist. Your colleague is an oncologist who wants your help explaining the basics of genetics to their patient, who will be undergoing genetic testing in the coming weeks for possible acute myeloid leukemia (AML) induced by the radiation she had several years ago for breast cancer. Write a 1,050- to 1,225-word memo to your colleague. Include the following in your memo: An explanation of the molecular structure of DNA and RNA, highlighting both similarities and differences  A description of the processes of transcription and translation An explanation of the differences between leading and lagging strands and how the DNA is replicated in each strand Reponses to the following common questions patients might ask about this type of genetic testing and genetic disorder: Does AML run in families? What genes are tested for?
Respond to the following in a minimum of 175 words: What are some potential consequences that could result if the processes of replication, transcription, and translation don’t function correctly? Provide an example of how you might explain these consequences in terms that patients might understand.
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