Chapter 21, Problem 21.64EP

Indicate whether each of the following statements describes a reversible competitive inhibitor, a reversible noncompetitive inhibitor, or an irreversible inhibitor. More than one answer may apply.

1. a. It bonds covalently to the enzyme active site.
2. b. The inhibitor effect can be reversed by the addition of more substrate.
3. c. Inhibitor structure must be somewhat similar to that of the substrate.
4. d. The inhibitor and substrate cannot bind to the enzyme simultaneously.