The detailed mechanism of the reactions of δ-lactone and β-lactone with ammonia yields hydroxyamide and β-amino acid respectively are to provided. Concept introduction: In the nucleophilic addition reaction, nucleophile adds first on the carbonyl carbon and the nucleophilic elimination reaction, the bond between C and O of leaving group breaks. Amines are more nucleophilic than water and alcohol so they react with carboxylic acid derivatives which yield amide. The carboxylic acid derivation undergoes nucleophilic addition of ester to produce the tetrahedral intermediate followed by the protonation of the negatively charged O atom.

Question

Want to see the full answer?

Answer 1

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 21, Problem 21.42P

Interpretation Introduction

Interpretation:

The detailed mechanism of the reactions of δ-lactone and β-lactone with ammonia yields hydroxyamide and β-amino acid respectively are to provided.

Concept introduction:

In the nucleophilic addition reaction, nucleophile adds first on the carbonyl carbon and the nucleophilic elimination reaction, the bond between C and O of leaving group breaks. Amines are more nucleophilic than water and alcohol so they react with carboxylic acid derivatives which yield amide. The carboxylic acid derivation undergoes nucleophilic addition of ester to produce the tetrahedral intermediate followed by the protonation of the negatively charged O atom.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

H2O2(aq) +3 I¯(aq) +2 H+(aq) → 13(aq) +2 H₂O(l)· ••• Experiment [H2 O2]o (M) [I]o (M) [H+]。 (M) Initial rate (M/s) 1 0.15 0.15 0.05 0.00012 234 0.15 0.3 0.05 0.00024 0.3 0.15 0.05 0.00024 0.15 0.15 0.1 0.00048 Calculate the overall order of this reaction using the table data.

The U. S. Environmental Protection Agency (EPA) sets limits on healthful levels of air pollutants. The maximum level that the EPA considers safe for lead air pollution is 1.5 μg/m³ Part A If your lungs were filled with air containing this level of lead, how many lead atoms would be in your lungs? (Assume a total lung volume of 5.40 L.) ΜΕ ΑΣΦ = 2.35 1013 ? atoms ! Check your rounding. Your final answer should be rounded to 2 significant figures in the last step. No credit lost. Try again.

Y= - 0.039 (14.01) + 0.7949

Answer 2

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 21, Problem 21.42P

Interpretation Introduction

Interpretation:

The detailed mechanism of the reactions of δ-lactone and β-lactone with ammonia yields hydroxyamide and β-amino acid respectively are to provided.

Concept introduction:

In the nucleophilic addition reaction, nucleophile adds first on the carbonyl carbon and the nucleophilic elimination reaction, the bond between C and O of leaving group breaks. Amines are more nucleophilic than water and alcohol so they react with carboxylic acid derivatives which yield amide. The carboxylic acid derivation undergoes nucleophilic addition of ester to produce the tetrahedral intermediate followed by the protonation of the negatively charged O atom.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 3

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 21, Problem 21.42P

Interpretation Introduction

Interpretation:

The detailed mechanism of the reactions of δ-lactone and β-lactone with ammonia yields hydroxyamide and β-amino acid respectively are to provided.

Concept introduction:

In the nucleophilic addition reaction, nucleophile adds first on the carbonyl carbon and the nucleophilic elimination reaction, the bond between C and O of leaving group breaks. Amines are more nucleophilic than water and alcohol so they react with carboxylic acid derivatives which yield amide. The carboxylic acid derivation undergoes nucleophilic addition of ester to produce the tetrahedral intermediate followed by the protonation of the negatively charged O atom.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 4

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 21, Problem 21.42P

Interpretation Introduction