BIOCHEMISTRY 2 TERM ACCESS
9th Edition
ISBN: 9781319402877
Author: BERG
Publisher: MAC HIGHER
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Chapter 21, Problem 13P
Interpretation Introduction
Interpretation:
The reason for the increased amount of glycogen in von Gierke disease (type I glycogen-storage disease) should be explained.
Concept introduction:
The von Gierke disease is a condition, in which the body is not able to breakdown the glycogen into glucose. Whenever energy is required in the body, glycogen is broken down to produce glucose to meet the energy demands.
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Consider the four graphs shown. In each graph, the solid blue curve represents the unmodified allosteric enzyme and the dashed
green curve represents the enzyme in the presence of the effector.
Identify which graphs correctly illustrate the effect of a negative modifier (allosteric inhibitor) and a positive modifier (allosteric
activator) on the velocity curve of an allosteric enzyme. Place the correct graph in the set of axes for each type of modifier.
Negative modifier
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Positive modifier
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Reaction velocity →→→→
Substrate concentration
Answer Bank
Consider the reaction:
phosphoglucoisomerase
Glucose 6-phosphate:
glucose 1-phosphate
After reactant and product were mixed and allowed to reach at 25 °C, the concentration of each compound at equilibrium
was measured:
[Glucose 1-phosphate] = 0.01 M
[Glucose 6-phosphate] = 0.19 M
Calculate Keq and AG°'.
Код
.0526
Incorrect Answer
7.30
AG°'
kJ mol-1
Incorrect Answer
Classify each phrase as describing kinases, phosphatases, neither, or both.
Kinases
Phosphatases
Neither
Both
Answer Bank
transfer phosphoryl groups to acidic amino acids in eukaryotes
may use ATP as a phosphoryl group donor
remove phosphoryl groups from proteins
catalyze reactions that are the reverse of dephosphorylation reactions
regulate the activity of other proteins
catalyze phosphorylation reactions
PKA as an example
turn off signaling pathways triggered by kinases
Chapter 21 Solutions
BIOCHEMISTRY 2 TERM ACCESS
Ch. 21 - Prob. 1PCh. 21 - Prob. 2PCh. 21 - Prob. 3PCh. 21 - Prob. 4PCh. 21 - Prob. 5PCh. 21 - Prob. 6PCh. 21 - Prob. 7PCh. 21 - Prob. 8PCh. 21 - Prob. 9PCh. 21 - Prob. 10P
Ch. 21 - Prob. 11PCh. 21 - Prob. 12PCh. 21 - Prob. 13PCh. 21 - Prob. 14PCh. 21 - Prob. 15PCh. 21 - Prob. 16PCh. 21 - Prob. 17PCh. 21 - Prob. 18PCh. 21 - Prob. 19PCh. 21 - Prob. 20PCh. 21 - Prob. 21PCh. 21 - Prob. 22PCh. 21 - Prob. 23PCh. 21 - Prob. 24PCh. 21 - Prob. 25PCh. 21 - Prob. 26PCh. 21 - Prob. 27PCh. 21 - Prob. 28PCh. 21 - Prob. 29PCh. 21 - Prob. 30PCh. 21 - Prob. 31PCh. 21 - Prob. 32PCh. 21 - Prob. 33PCh. 21 - Prob. 34PCh. 21 - Prob. 35PCh. 21 - Prob. 36PCh. 21 - Prob. 37PCh. 21 - Prob. 38PCh. 21 - Prob. 39PCh. 21 - Prob. 40PCh. 21 - Prob. 41PCh. 21 - Prob. 42PCh. 21 - Prob. 43PCh. 21 - Prob. 44PCh. 21 - Prob. 45PCh. 21 - Prob. 46P
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