BIOCHEMISTRY 2 TERM ACCESS
BIOCHEMISTRY 2 TERM ACCESS
9th Edition
ISBN: 9781319402877
Author: BERG
Publisher: MAC HIGHER
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Chapter 21, Problem 42P
Interpretation Introduction

(a)

Interpretation:

The results obtained with the mutant should be explained.

Concept introduction:

Glycogen phosphorylase catalyzes the cleavage of the terminal alpha-1,4-glycosidic bond of glycogen polymer releasing glucose-1-phosphate. The most important regulatory site in glycogen phosphorylase is Serine 14 residue. Phosphorylation of this ser-14 residue activate phosphorylase b form to phosphorylase a form.

Interpretation Introduction

(b)

Interpretation:

The effect of substituting aspartic acid for serine should be predicted.

Concept introduction:

Glycogen phosphorylase catalyzes the cleavage of the terminal alpha-1,4-glycosidic bond of glycogen polymer releasing glucose-1-phosphate. The most important regulatory site in glycogen phosphorylase is Serine 14 residue. Phosphorylation of this ser-14 residue activate phosphorylase b form to phosphorylase a form.

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