Organic Chemistry
Organic Chemistry
7th Edition
ISBN: 9780321803221
Author: Paula Y. Bruice
Publisher: Prentice Hall
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Chapter 20.7, Problem 16P
Interpretation Introduction

Interpretation:

The difference in the boiling point of imidazole and N-methylimidazole has to be explained.

Concept Introduction:

Imidazole is the aromatic compound and also the heterocyclic ring of histidine. It exists in both protonated and non-protonated form at pH=7.4. The lone pair on first nitrogen are a part of the pi cloud as they are present in p orbital whereas the lone pair electrons on third nitrogen are not a part of pi cloud because they are perpendicular to the p orbitals.

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