Anatomy & Physiology (6th Edition)
6th Edition
ISBN: 9780134156415
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
expand_more
expand_more
format_list_bulleted
Concept explainers
Videos
Textbook Question
Chapter 20.4, Problem 9CYU
What event (or observation) signals that a B or T cell has achieved immunocompetence?
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
The diagram below illustrates a quorum sensing pathway from Staphylococcus aureus. Please answer the following questions.
1. Autoinduction is part of the quorum sensing system. Which promoter (P2 or P3) is critical for autoinduction?
2)This staphylococcus aureus grows on human wounds, causing severe infections. You would like to start a clinical trial to treat these wound infections. Please describe:
a) What molecule do you recommend for the trial. Why?
b) Your trial requires that Staphylococcus aureus be isolated from the wound and submitted to genome sequencing before admittance. Why? What are you testing for?
3) If a mutation arises where the Promoter P3 is constitutively active, how would that influence sensitivity to AIP? Please explain your rationale.
4) This pathway is sensitive to bacterial cell density. Describe two separate mutation that would render the pathway active independent of cell density. Briefly explain your rationale.
Mutation 1
Mutation 2
There is currently a H5N1 cattle outbreak in North America.
According to the CDC on Feb 26*: "A multistate outbreak of HPAI A(H5N1) bird flu in dairy cows was first reported on March 25, 2024. This is the first time that these bird flu viruses had been found in cows. In the United States, since 2022, USDA has reported HPAI A(H5N1) virus detections in more than 200 mammals."
List and describe two mechanisms that could lead to this H5N1 influenza strain evolving to spread in human:
Mechanisms 1:
Mechanisms 2:
For the mutations to results in a human epidered they would need to change how the virus interacts with the human host. In the case of mutations that may promote an epidemic, provide an example for:
a protein that might incur a mutation:
how the mutation would change interactions with cells in the respiratory tract (name the receptor on human cells)
List two phenotypic consequence from this mutation that would increase human risk
You have a bacterial strain with the CMU operon:
a) As shown in the image below, the cmu operon encodes a peptide (Pep1), as well as a
kinase and regulator corresponding to a two-component system. The cmu operon is
activated when Pep 1 is added to the growth media.
Pep1 is a peptide that when added extracellularly leads to activation of the Cmu operon.
Pep1 cmu-kinase cmu-regulator
You also have these genetic components in other strains:
b) An alternative sigma factor, with a promoter activated by the cmu-regulator, that control a
series of multiple operons that together encode a transformasome (cellular machinery
for transformation).
c) the gene cl (a repressor).
d) the promoter X, which includes a cl binding site (and in the absence of cl is active).
e) the gene gp (encoding a green fluorescence protein).
Using the cmu operon as a starting point, and assuming you can perform cloning to rearrange
any of these genomic features, how would you use one or more of these to modify the…
Chapter 20 Solutions
Anatomy & Physiology (6th Edition)
Ch. 20.1 - What distinguishes the innate defense system from...Ch. 20.1 - What is the first line of defense against disease?Ch. 20.2 - What is opsonization and how does it help...Ch. 20.2 - Under what circumstances might NK cells kill our...Ch. 20.2 - What are the cardinal signs of inflammation and...Ch. 20.3 - Name three key characteristics of adaptive...Ch. 20.3 - What is the difference between a complete antigen...Ch. 20.3 - What marks a cell as self as opposed to nonselfCh. 20.4 - What event (or observation) signals that a B or T...Ch. 20.4 - Which of the following T cells would survive...
Ch. 20.4 - Prob. 11CYUCh. 20.4 - In clonal selection, who does the selecting? What...Ch. 20.5 - Why is the secondary response to an antigen so...Ch. 20.5 - Prob. 14CYUCh. 20.5 - Which class of antibody is most abundant in blood?...Ch. 20.5 - List four ways in which antibodies can bring about...Ch. 20.5 - Prob. 17CYUCh. 20.6 - Class II MHC proteins display what kind of...Ch. 20.6 - Which type of T cell is the most important in both...Ch. 20.6 - Describe the killing mechanism of cytotoxic T...Ch. 20.7 - Prob. 21CYUCh. 20.7 - Prob. 22CYUCh. 20 - All of the following are considered innate body...Ch. 20 - The process by which neutrophils squeeze through...Ch. 20 - Antibodies released by plasma cells are involved...Ch. 20 - Which of the following antibodies can fix...Ch. 20 - Which antibody class is abundant in body...Ch. 20 - Small molecules that must combine with large...Ch. 20 - Lymphocytes that develop immunocompetence in the...Ch. 20 - Cells that can directly attack target cells...Ch. 20 - Prob. 9MCCh. 20 - The cell type most often invaded by HIV is a(n)...Ch. 20 - Complement fixation promotes all of the following...Ch. 20 - Using the letters from column B, match the cell...Ch. 20 - Besides acting as mechanical barriers, the skin...Ch. 20 - Explain why attempts at phagocytosis are not...Ch. 20 - What is complement? How does it cause bacterial...Ch. 20 - Interferons are referred to as antiviral proteins....Ch. 20 - Differentiate between humoral and cellular...Ch. 20 - Although the adaptive immune system has two arms,...Ch. 20 - Define immunocompetence and self-tolerance. How is...Ch. 20 - Differentiate between a primary and a secondary...Ch. 20 - Prob. 21SAQCh. 20 - What is the role of the variable regions of an...Ch. 20 - Name the five antibody classes and describe where...Ch. 20 - How do antibodies help defend the body?Ch. 20 - Do vaccines produce active or passive humoral...Ch. 20 - Prob. 26SAQCh. 20 - Describe the specific roles of helper, regulatory,...Ch. 20 - Prob. 28SAQCh. 20 - Prob. 29SAQCh. 20 - What events can result in autoimmune disease?Ch. 20 - Prob. 1CCSCh. 20 - Prob. 2CCSCh. 20 - Prob. 3CCSCh. 20 - Prob. 4CCSCh. 20 - Remember Mr. Ayers, the bus driver from Chapter...
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- You have identified a new species of a Gram-positive bacteria. You would like to screen their genome for all proteins that are covalently linked to the cell wall. You have annotated the genome, so that you identified all the promoters, operons, and genes sequences within the operons. Using these features, what would you screen for to identify a set of candidates for proteins covalently linked to the bacterial cell wall.arrow_forwardBelow is a diagram from a genomic locus of a bacterial genome. Each arrow represents a coding region, and the arrowheads indicate its orientation in the genome. The numbers are randomly assigned. Draw the following features on the diagram, and explain your rationale for each feature: 10 12 合會會會會長 6 a) Expected transcriptions, based on known properties of bacterial genes and operons. How many proteins are encoded in each of the transcripts? b) Location of promoters (include rationale) c) Location of transcriptional terminators (include rationale) d) Locations of Shine-Dalgarno sequences (include rationale)arrow_forwardSample excuse letter in school class for the reasons of headaches and dysmenorrhea caused by menstrual cyclearrow_forward
- How do the muscles on the foot work to balance on an ice skate, specifically the triangle of balance and how does it change when balancing on an ice skate? (Refer to anatomy, be specific)arrow_forwardWhich of the following is NOT an example of passive immunization? A. Administration of tetanus toxoid B. Administration of hepatitis B immunoglobulin C. Administration of rabies immunoglobulin D. Transfer of antibodies via plasma therapyarrow_forwardTranscription and Translation 1. What is the main function of transcription and translation? (2 marks) 2. How is transcription different in eukaryotic and prokaryotic cells? (2 marks) 3. Explain the difference between pre-mRNA and post-transcript mRNA. (2 marks) 4. What is the function of the following: (4 marks) i. the cap ii. spliceosome iii. Poly A tail iv. termination sequence 5. What are advantages to the wobble feature of the genetic code? (2 marks) 6. Explain the difference between the: (3 marks) i. A site & P site ii. codon & anticodon iii. gene expression and gene regulation 7. Explain how the stop codon allows for termination. (1 mark) 8. In your own words, summarize the process of translation. (2 marks)arrow_forward
- In this activity you will research performance enhancers that affect the endocrine system or nervous system. You will submit a 1 page paper on one performance enhancer of your choice. Be sure to include: the specific reason for use the alleged results on improving performance how it works how it affect homeostasis and improves performance any side-effects of this substancearrow_forwardNeurons and Reflexes 1. Describe the function of the: a) dendrite b) axon c) cell body d) myelin sheath e) nodes of Ranvier f) Schwann cells g) motor neuron, interneuron and sensory neuron 2. List some simple reflexes. Explain why babies are born with simple reflexes. What are they and why are they necessary. 3. Explain why you only feel pain after a few seconds when you touch something very hot but you have already pulled your hand away. 4. What part of the brain receives sensory information? What part of the brain directs you to move your hand away? 5. In your own words describe how the axon fires.arrow_forwardMutations Here is your template DNA strand: CTT TTA TAG TAG ATA CCA CAA AGG 1. Write out the complementary mRNA that matches the DNA above. 2. Write the anticodons and the amino acid sequence. 3. Change the nucleotide in position #15 to C. 4. What type of mutation is this? 5. Repeat steps 1 & 2. 6. How has this change affected the amino acid sequence? 7. Now remove nucleotides 13 through 15. 8. Repeat steps 1 & 2. 9. What type of mutation is this? 0. Do all mutations result in a change in the amino acid sequence? 1. Are all mutations considered bad? 2. The above sequence codes for a genetic disorder called cystic fibrosis (CF). 3. When A is changed to G in position #15, the person does not have CF. When T is changed to C in position #14, the person has the disorder. How could this have originated?arrow_forward
- hoose a scientist(s) and research their contribution to our derstanding of DNA structure or replication. Write a one page port and include: their research where they studied and the time period in which they worked their experiments and results the contribution to our understanding of DNA cientists Watson & Crickarrow_forwardhoose a scientist(s) and research their contribution to our derstanding of DNA structure or replication. Write a one page port and include: their research where they studied and the time period in which they worked their experiments and results the contribution to our understanding of DNA cientists Watson & Crickarrow_forward7. Aerobic respiration of a protein that breaks down into 12 molecules of malic acid. Assume there is no other carbon source and no acetyl-CoA. NADH FADH2 OP ATP SLP ATP Total ATP Show your work using dimensional analysis here: 3arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Human Biology (MindTap Course List)BiologyISBN:9781305112100Author:Cecie Starr, Beverly McMillanPublisher:Cengage Learning
Concepts of BiologyBiologyISBN:9781938168116Author:Samantha Fowler, Rebecca Roush, James WisePublisher:OpenStax College
Human Physiology: From Cells to Systems (MindTap ...BiologyISBN:9781285866932Author:Lauralee SherwoodPublisher:Cengage Learning
Human Biology (MindTap Course List)
Biology
ISBN:9781305112100
Author:Cecie Starr, Beverly McMillan
Publisher:Cengage Learning
Concepts of Biology
Biology
ISBN:9781938168116
Author:Samantha Fowler, Rebecca Roush, James Wise
Publisher:OpenStax College
Human Physiology: From Cells to Systems (MindTap ...
Biology
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Cengage Learning
Immune System Diseases and Disorders; Author: Heather Davis;https://www.youtube.com/watch?v=3lIkxNv7MVI;License: Standard youtube license