Human Biology (MindTap Course List)
Human Biology (MindTap Course List)
11th Edition
ISBN: 9781305112100
Author: Cecie Starr, Beverly McMillan
Publisher: Cengage Learning
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Chapter 20, Problem 3RQ

What evidence indicates that a trait is coded by a dominant allele on an autosome?

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In a woman who is a carrier of a mutant OTC deficiency allele, her sons who receive the mutant allele will be affected and her daughters will be carriers who may or may not be symptomatic, depending on random X inactivation in the liver. 1) Is this a single gene inheritance or multifactorial disease? 2) Is there a strong genetic or environmental cause to the development of this disease? If both genetic and environmental causes are implicated, you have to indicate each of them separately.
Explain how a loss-of-function allele in a gene encoding a cohesin protein could be dominant to itswild-type counterpart.
Why does a loss or an excess in genetic material lead to the expression of an abnormal phenotype?
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Mitochondrial mutations; Author: Useful Genetics;https://www.youtube.com/watch?v=GvgXe-3RJeU;License: CC-BY