The missing compounds A through D are to be supplied. Concept introduction: The starting amide undergoes hydrolysis to produce carboxylic acid , A . Diazomethane converts the carboxylic acid to a methyl ester. This methyl ester is reduced by the reducing agent DIBAH B to an aldehyde . This aldehyde undergoes direct addition by Grignard reagent to make alcohol C . The alcohol is then deprotonated to make the alkoxide anion, which is then acylated with acetic anhydride, yielding the target compound D .

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Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 20, Problem 20.63P

Interpretation Introduction

Interpretation:

The missing compounds A through D are to be supplied.

Concept introduction:

The starting amide undergoes hydrolysis to produce carboxylic acid, A. Diazomethane converts the carboxylic acid to a methyl ester. This methyl ester is reduced by the reducing agent DIBAH B to an aldehyde. This aldehyde undergoes direct addition by Grignard reagent to make alcohol C. The alcohol is then deprotonated to make the alkoxide anion, which is then acylated with acetic anhydride, yielding the target compound D.

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Part VII. Below are the 'HNMR, 13 C-NMR, COSY 2D- NMR, and HSQC 2D-NMR (similar with HETCOR but axes are reversed) spectra of an organic compound with molecular formula C6H1003 - Assign chemical shift values to the H and c atoms of the compound. Find the structure. Show complete solutions. Predicted 1H NMR Spectrum 4.7 4.6 4.5 4.4 4.3 4.2 4.1 4.0 3.9 3.8 3.7 3.6 3.5 3.4 3.3 3.2 3.1 3.0 2.9 2.8 2.7 2.6 2.5 2.4 2.3 2.2 2.1 2.0 1.9 1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1 f1 (ppm) Predicted 13C NMR Spectrum 100 f1 (ppm) 30 220 210 200 190 180 170 160 150 140 130 120 110 90 80 70 -26 60 50 40 46 30 20 115 10 1.0 0.9 0.8 0 -10

Answer 2

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Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 20, Problem 20.63P

Interpretation Introduction

Interpretation:

The missing compounds A through D are to be supplied.

Concept introduction:

The starting amide undergoes hydrolysis to produce carboxylic acid, A. Diazomethane converts the carboxylic acid to a methyl ester. This methyl ester is reduced by the reducing agent DIBAH B to an aldehyde. This aldehyde undergoes direct addition by Grignard reagent to make alcohol C. The alcohol is then deprotonated to make the alkoxide anion, which is then acylated with acetic anhydride, yielding the target compound D.

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Answer 3

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Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 20, Problem 20.63P

Interpretation Introduction

Interpretation:

The missing compounds A through D are to be supplied.

Concept introduction:

The starting amide undergoes hydrolysis to produce carboxylic acid, A. Diazomethane converts the carboxylic acid to a methyl ester. This methyl ester is reduced by the reducing agent DIBAH B to an aldehyde. This aldehyde undergoes direct addition by Grignard reagent to make alcohol C. The alcohol is then deprotonated to make the alkoxide anion, which is then acylated with acetic anhydride, yielding the target compound D.

Expert Solution & Answer

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Check out a sample textbook solution

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Answer 4

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 20, Problem 20.63P

Interpretation Introduction