Chapter 20, Problem 20.61P

Interpretation Introduction

Interpretation:

The missing compound from A to D for the given reaction is to be provided.

Concept introduction:

The reactions involved electron-rich and electron-poor species which give functional group transformation. In Haloform reaction, a methyl ketone $\left({\text{RCOCH}}_{\text{3}}\right)$ undergoes acyl substitution when treated with molecular halogen $\left({\text{x}}_{\text{2}}\right)$ in aqueous $\text{NaOH}$ producing a carboxylic acid. Whereas, ${\text{LiAlH}}_{\text{4}}$ is a much strong reducing agent that can reduce a carboxylic acid to a primary alcohol. The bromination with ${\text{PBr}}_{\text{3}}$ replaces the $\text{OH}$ group with $\text{Br}$ to make alkyl halide. And this alkyl halide used in the Gabriel synthesis to produce primary amine.