The meaning of the statement referring post translational modifications as “Nature’s escape from genetic imprisonment” should be explained. Concept introduction: Post-translational modifications are mechanisms which amino acid residues in a protein are covalently modified after protein biosynthesis. For example, phosphorylation is most common post translational modification. Glycosylation and lipidation are also post translational modifications. Proteins are modified by modifying existing functional group of a standard amino acid or adding a new functional group.

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Chapter 2, Problem 37P

Interpretation Introduction

Interpretation:

The meaning of the statement referring post translational modifications as “Nature’s escape from genetic imprisonment” should be explained.

Concept introduction:

Post-translational modifications are mechanisms which amino acid residues in a protein are covalently modified after protein biosynthesis. For example, phosphorylation is most common post translational modification. Glycosylation and lipidation are also post translational modifications. Proteins are modified by modifying existing functional group of a standard amino acid or adding a new functional group.

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