Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN: 9781285866932
Author: Lauralee Sherwood
Publisher: Cengage Learning
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Chapter 2, Problem 2TAHL
Summary Introduction
To write:
The consequences of cyanide poisoning.
Introduction:
Oxidative phosphorylation refers to the process by which ATP is synthesized with electron-released energy during its transfer to O2. It involves two protein groups in the inner mitochondrial membrane: electron transfer system and ATP synthase. The electron transport system comprises of electron carrier systems in four large stationary protein complexes numbered I, II, III, IV and two small, extremely mobile, cytochrome c and ubiquinone.
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Although the outer mitochondrial membrane is permeable to all small molecules, the inner mitochondrial membrane is essentially impermeable in the absence of specific transport proteins. Consider this information answer: The ATP generated by oxidative respiration is used throughout the cell. The majority of ATP production occurs in the mitochondrial matrix. How do you think ATP is made accessible to enzymes in the cytosol and other organelles?
Figure 4.15 Cyanide inhibits cytochrome c oxidase, a component of the electron transport chain. If cyanide poisoning occurs, would you expect the pH of the intermembrane space to increase or decrease? What affect would cyanide have on ATP synthesis?
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Chapter 2 Solutions
Human Physiology: From Cells to Systems (MindTap Course List)
Ch. 2.1 - State the principles of the cell theory.Ch. 2.1 - Prob. 2CYUCh. 2.2 - State the functions of DNA and the different types...Ch. 2.2 - Prob. 2CYUCh. 2.2 - Prob. 3CYUCh. 2.3 - Prob. 1CYUCh. 2.3 - Discuss the structure and function of a ribosome.Ch. 2.3 - Prob. 3CYUCh. 2.3 - Prob. 4CYUCh. 2.4 - Describe the structure and functions of a Golgi...
Ch. 2.4 - Prob. 2CYUCh. 2.4 - Prob. 3CYUCh. 2.5 - Prob. 1CYUCh. 2.5 - Prob. 2CYUCh. 2.5 - Prob. 3CYUCh. 2.6 - Prob. 1CYUCh. 2.6 - Prob. 2CYUCh. 2.7 - Prob. 1CYUCh. 2.7 - Prob. 2CYUCh. 2.7 - Prob. 3CYUCh. 2.7 - Prob. 4CYUCh. 2.8 - Prob. 1CYUCh. 2.8 - Prob. 2CYUCh. 2.9 - Prob. 1CYUCh. 2.9 - Prob. 2CYUCh. 2.10 - List the three types of cytoskeletal elements and...Ch. 2.10 - Explain how motor proteins transport proteins...Ch. 2.10 - Prob. 3CYUCh. 2.10 - Prob. 4CYUCh. 2 - Prob. 1RECh. 2 - Prob. 2RECh. 2 - Prob. 3RECh. 2 - Prob. 4RECh. 2 - Prob. 5RECh. 2 - Prob. 6RECh. 2 - Prob. 7RECh. 2 - Prob. 8RECh. 2 - Prob. 9RECh. 2 - Using the answer code on the right, indicate which...Ch. 2 - Prob. 11RECh. 2 - Prob. 1UCCh. 2 - Prob. 2UCCh. 2 - Prob. 3UCCh. 2 - Compare exocytosis and endocytosis. Define...Ch. 2 - Prob. 5UCCh. 2 - Compare lysosomes with peroxisomes.Ch. 2 - Distinguish among cellular respiration, oxidative...Ch. 2 - Prob. 8UCCh. 2 - Prob. 9UCCh. 2 - Cells expend energy on what three categories of...Ch. 2 - Prob. 11UCCh. 2 - Prob. 1SQECh. 2 - Prob. 2SQECh. 2 - Prob. 3SQECh. 2 - Calculate the number of cells in the body of an...Ch. 2 - Prob. 5SQECh. 2 - Applying Clinical Reasoning Kevin S. and his wife...Ch. 2 - The stomach has two types of exocrine secretory...Ch. 2 - Prob. 2TAHLCh. 2 - Prob. 3TAHLCh. 2 - Why do you think a person is able to perform...Ch. 2 - Prob. 5TAHL
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
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- In the pathways of cell metabolism, 1) glycolysis does NOT occur in the mitochondria, AND 2) the proton gradient in oxidative phosphorylation occurs through a PASSIVE transport process. True Falsearrow_forwardCyanide acts by blocking the flow of electrons in the electron transport system. What happens to ATP production and oxygen consumption in mitochondria when cells are poisoned with cyanide? Do the rates of oxygen consumption and ATP formation increase, decrease, or remain constant?arrow_forwardDescribe the main functions of the different components of the ATP synthase enzyme in the mitochondrion. A structurally similar enzyme is responsible for the acidification of lysosomes and endosomes. Given what you know about the mechanism of ATP synthesis, explain how this acidification might occur.arrow_forward
- The electron transport chain makes no ATP directly. Instead, it eases the fall of electrons from food to oxygen, breaking a large free-energy drop into a series of smaller steps that release energy in manageable amounts, step by step. How does the mitochondrion (or the plasma membrane in prokaryotes) couple this electron transport and energy release to ATP synthesis?arrow_forwardConsider a 24:1 △cis-9 fatty acid in the mitochondrion. For each fatty acid given, determine the following. Total number of ATP deducted Total net ATParrow_forwardThe majority of ATP production in aerobic cellular respiration occurs within the mitochondria during electron transport. In this phase of cellular respiration, NADH and FADH, are oxidized to become NAD+ and FAD+. The protons and electrons released during this axidation are used to establisha chemiosmotic gradient in the mitochondrial intermembrane space. The potential established by this gradient is used to convert mechanical energy into the chemical energy needed to join an inorganic phosphate on to ADP, thus creating ATP. Mitochondrial DNA Lamela er membrane Inner boundary membrane - Cristal membrane Matrin- Cristae Matrix granule Ribosome ATP synthase Intermembrane space Intracristal space Peripheral space Outer membrane Parins Mitochondrion structure by Kelvin13 (CC BY-SA 3.0) Outer membrane Cyt e ATP Synthase NADH NAD+H ATP Citric ADP acid cycle Matrix Suecinate Fumee Inner membrane Intermembrane space Mitochondrial electron transport chain by Fvasconcello (CCO) a. Analyze why…arrow_forward
- Figure 7.11 Dinitrophenol (DNP) is an "uncoupler" that makes the inner mitochondrial membrane "leaky" to protons. It was used until 1938 as a weight- loss drug. What effect would you expect DNP to have on the change in pH across the inner mitochondrial membrane? Why do you think this might be an effective weight-loss drug? Intermembrane space Mitochondrial matrix ATP Synthase ADP Inner mitochondrial membrane ATP Figure 7.11 ATP synthase is a complex, molecular machine that uses a proton (H) gradient to form ATP from ADP and inorganic phosphate (Pi). (Credit: modification of work by Klaus Hoffmeier)arrow_forwardWhat would be the effect on ATP production during chemiosmosis and oxidative phorphorylation, if the pH within the inner membrane space of the mitochondrion were decreased, assuming no effect of pH on the structure of proteins in the membrane? a) it would increase b) it would decrease c)it would stay the samearrow_forwardYou have discovered a mutant cell whose glycolytic pathway is shorter because of a new enzyme catalyzing the reaction: NAD+ NADH + H* Glyceraldehyde 3-phosphate + H20 3-phosphoglycerate Please explain why this mutant cell would die under anaerobic conditions but not aerobic conditions. Enter your answer herearrow_forward
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