Biochemistry: Concepts and Connections
Biochemistry: Concepts and Connections
1st Edition
ISBN: 9780321839923
Author: Dean R. Appling, Spencer J. Anthony-Cahill, Christopher K. Mathews
Publisher: PEARSON
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Chapter 2, Problem 18P

Histidine is an amino acid with three titratable groups: an -NH3+ group (pKa = 9.2) —COOH group (pKa = 1.8). and an imidazole (amine-like) group (Pka = 6.0). The titration curve for histidine is shown below with four points highlighted.
a. Identify which point on the titration curve corresponds to the pKa for each of the titratable groups, and which point corresponds to the pl. Explain your choices.
b. Calculate the value of pl for histidine.

Chapter 2, Problem 18P, Histidine is an amino acid with three titratable groups: an -NH3+ group (pKa = 9.2) —COOH group (pKa

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Biomolecules - Protein - Amino acids; Author: Tutorials Point (India) Ltd.;https://www.youtube.com/watch?v=ySNVPDHJ0ek;License: Standard YouTube License, CC-BY