Principles of Anatomy and Physiology
15th Edition
ISBN: 9781119329398
Author: Gerard J Tortora, Bryan Derrickson
Publisher: John Wiley & Sons Inc
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Chapter 2, Problem 15CP
How do bicarbonate ions prevent build-up of excess H+?
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The following table is from Kumar et. al. Highly Selective Dopamine D3 Receptor (DR) Antagonists and Partial Agonists Based on Eticlopride and the D3R Crystal Structure: New Leads for Opioid Dependence Treatment. J. Med Chem 2016.
The following figure is from Caterina et al. The capsaicin receptor: a heat activated ion channel in the
pain pathway. Nature, 1997. Black boxes indicate capsaicin, white circles indicate resinferatoxin.
You are a chef in a fancy new science-themed restaurant. You have a recipe that calls for 1 teaspoon of resinferatoxin, but you feel uncomfortable serving foods with "toxins" in them. How much capsaicin could you substitute instead?
What protein is necessary for packaging acetylcholine into synaptic vesicles?
Chapter 2 Solutions
Principles of Anatomy and Physiology
Ch. 2 - List the names and chemical symbols of the 12 most...Ch. 2 - What are the atomic number, mass number, and...Ch. 2 - Define isotopes and free radicals.Ch. 2 - Which electron shell is the valence shell of an...Ch. 2 - Compare the properties of ionic, covalent, and...Ch. 2 - What information is conveyed when you write the...Ch. 2 - Checkpoint 7:
What is the relationship between...Ch. 2 - Compare potential energy and kinetic energy.Ch. 2 - Checkpoint 9:
How do catalysts affect activation...Ch. 2 - How are anabolism and catabolism related to...
Ch. 2 - Why are oxidation–reduction reactions important?Ch. 2 - Checkpoint 12:
How do inorganic compounds differ...Ch. 2 - Describe two ways to express the concentration of...Ch. 2 - Prob. 14CPCh. 2 - Checkpoint 15:
How do bicarbonate ions prevent...Ch. 2 - Prob. 16CPCh. 2 - Prob. 17CPCh. 2 - How are carbohydrates classified?Ch. 2 - Prob. 19CPCh. 2 - Prob. 20CPCh. 2 - Checkpoint 21:
Distinguish among saturated,...Ch. 2 - Define a protein. What is a peptide bond?Ch. 2 - What are the different levels of structural...Ch. 2 - Why are enzymes important?Ch. 2 - Checkpoint 25:
How do DNA and RNA differ?
Ch. 2 - Prob. 26CPCh. 2 - In the reaction catalysed by ATP synthase, what...Ch. 2 - CTQ 1: Your best friend has decided to begin...Ch. 2 - CTQ 2:
A 4-month-old baby is admitted to the...Ch. 2 - CTQ 3:
During chemistry lab, Maria places sucrose...
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- 1. Match each vocabulary term to its best descriptor A. affinity B. efficacy C. inert D. mimic E. how drugs move through body F. how drugs bind Kd Bmax Agonist Antagonist Pharmacokinetics Pharmacodynamicsarrow_forward50 mg dose of a drug is given orally to a patient. The bioavailability of the drug is 0.2. What is the volume of distribution of the drug if the plasma concentration is 1 mg/L? Be sure to provide units.arrow_forwardDetermine Kd and Bmax from the following Scatchard plot. Make sure to include units.arrow_forward
- Choose a catecholamine neurotransmitter and describe/draw the components of the synapse important for its signaling including synthesis, packaging into vesicles, receptors, transporters/degradative enzymes. Describe 2 drugs that can act on this system.arrow_forwardThe following figure is from Caterina et al. The capsaicin receptor: a heat activated ion channel in the pain pathway. Nature, 1997. Black boxes indicate capsaicin, white circles indicate resinferatoxin. a) Which has a higher potency? b) Which is has a higher efficacy? c) What is the approximate Kd of capsaicin in uM? (you can round to the nearest power of 10)arrow_forwardWhat is the rate-limiting-step for serotonin synthesis?arrow_forward
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