Biology
Biology
12th Edition
ISBN: 9780134813448
Author: Audesirk, Teresa, Gerald, Byers, Bruce E.
Publisher: Pearson,
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Chapter 19.1, Problem 1CSC

Origin of a Killer

Analysis of nucleotide sequences was absolutely required to construct the phylogeny of viruses that revealed the ancestor of HIV. The closely related viruses included in the phylogeny are all but indistinguishable on the basis or appearance and structure; the differences between them are revealed only by their nucleotide sequences. Thus, scientific sleuthing about the origin of HIV would have been impossible before the modern era or routine DNA sequencing.

DNA analysis has also shown that HIV is a member of a group called the lentiviruses. How do taxa get their names? can the names tell us anything about the evolutionary histories of taxa?

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Researchers have recently discovered giant viruses that are 1 μm in length, the same size as some bacterial cells. The genomes of these viruses contain over 2 million base pairs of DNA, which is more DNA than is found in many bacterial genomes, and their genomes contain hundreds—in some cases, thousands—of genes. Given these observations and what you know about viruses, should viruses be considered living or nonliving? Give arguments for and against considering viruses as living organisms.
why testing known inhibitors such as the HIV-1 protease inhibitors nelfinavir and atazanavir used in this experiment, is beneficial for creation of new antiviral drugs. Is it due to conserved viral DNA or something else entirely? nature.com/articles/s41467-021-20900-6
This virus does not conform to the central dogma of molecular biology. Explain the central dogma and how the virus behaves differently. How should the patient to treated? Can the treatments cure the disease?
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