Biology: The Unity and Diversity of Life
Biology: The Unity and Diversity of Life
15th Edition
ISBN: 9780357093795
Author: STARR
Publisher: CENGAGE LEARNING (CUSTOM)
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Chapter 19, Problem 3DAA

Antibiotic Effects on Mitochondria Tetracyclines are antibiotics that inactivate bacterial ribosomes. Knowing that mitochondria evolved from bacteria, researchers suspected tetracyclines might affect mitochondria by harming their ribosomes. FIGURE 19. 11 shows the effects of an experiment in which mice were given either tetracycline or a control antibiotic that affects cell wall production. After 10 days of treatment, the function of mitochondria in the mice was assessed.

Chapter 19, Problem 3DAA, Antibiotic Effects on Mitochondria Tetracyclines are antibiotics that inactivate bacterial

FIGURE 19.11 Effects of tetracycline on mitochondria. Mice received low-dose tetracycline, high-dose tetracycline, or a control antibiotic that targets bacterial cell walls. Mitochondrial function was assessed by looking at oxygen consumption rate and ATP content in homogenized mouse livers. Bar graphs show means with standard error. An * indicates a statistically significant difference between the experimental and the control treatments.

Why was a control antibiotic used, rather than using untreated mice as the control?

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