EBK GENETICS: FROM GENES TO GENOMES
EBK GENETICS: FROM GENES TO GENOMES
6th Edition
ISBN: 9781260041255
Author: HARTWELL
Publisher: MCGRAW HILL BOOK COMPANY
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Chapter 19, Problem 36P

It is crucial to the development of Drosophila that the Hox genes must not only be on where they should be expressed, but also that they must be off where they should not be expressed. Thus, in addition to enhancers, the Hox genes are controlled by silencers—elements like enhancers that bind only repressors. This fact was discovered by zygotic mutations in about 30 so-called Polycomb group (PcG) genes. Embryos homozygous for loss-of-function mutations in any one of the PcG genes have a similar mutant phenotype: As seen in the accompanying figure, parasegments whose identities are controlled by BX-C genes are all transformed into the most posterior abdominal parasegment (PS13):

a. What types of proteins do you think that the PcG genes encode?
b. Explain the mutant phenotype of the embryos lacking PcG proteins..

Chapter 19, Problem 36P, It is crucial to the development of Drosophila that the Hox genes must not only be on where they

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Chapter 19 Solutions

EBK GENETICS: FROM GENES TO GENOMES

Ch. 19 - Drosophila researchers have collected many strains...Ch. 19 - As an alternative to random mutagenesis,...Ch. 19 - A C. elegans nematode gene called par-1 helps to...Ch. 19 - The molecular identity of the fruit fly rugose...Ch. 19 - To determine the focus of action of boss,...Ch. 19 - Suppose a particular gene is required for early...Ch. 19 - Researchers have exploited Minute mutations in...Ch. 19 - Some ts alleles are temperature sensitive during...Ch. 19 - The following figure shows the temperature-shift...Ch. 19 - A temperature-sensitive allele of the gene...Ch. 19 - Hypomorphic alleles of a pleiotropic gene...Ch. 19 - In addition to the maternal effect genes that...Ch. 19 - The yan gene encodes a transcription factor that...Ch. 19 - Recall from Chapter 17 that in Drosophila, sex...Ch. 19 - a. Explain the difference between maternal...Ch. 19 - In the 1920s, Arthur Boycott, working with the...Ch. 19 - The Drosophila mutant screen shown on the...Ch. 19 - Some genes are required both zygotically and...Ch. 19 - How would a human with a mutation in a maternal...Ch. 19 - One important demonstration that Bicoid is an...Ch. 19 - The hunchback gene contains a 5 transcriptional...Ch. 19 - In flies developing from eggs laid by a...Ch. 19 - Wild-type embryos and mutant embryos lacking the...Ch. 19 - The Drosophila even-skipped eve gene has four...Ch. 19 - In Drosophila with loss-of-function mutations...Ch. 19 - It is crucial to the development of Drosophila...Ch. 19 - In the plant Arabidopsis thaliana, every flower is...
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