To determine: The histone H3 modifications that are associated with the activation of the gene.
Introduction: Histone modifications take place at specific amino acids in the N-terminal tail of histones H3, H4, 2A, and 2B.
To determine: The H3 modifications that are associated with repression of gene expression.
Introduction: The sum of the complex patterns and interactions within the histone molecules is known as the histone code.
(a)
To determine: Whether there are any overlaps on the lists of H3 modifications.
Introduction: Over twenty different chemical modifications can be made to histones. The major alterations include the addition of acetyl, phosphate, and methyl groups.
(b)
To determine: Whether the overlaps can be explained by different modifications.
Introduction: Histone modifications are covalent posttranscriptional modifications of amino acids near the N-terminal ends of histone proteins.
(c)
To determine: The other way to explain the overlaps.
Introduction: Amino acids are considered as building blocks of protein. Lysine is an amino acid. The process of formation of proteins from RNA is known as translation.
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Concepts of Genetics (12th Edition)
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