Concepts of Genetics (12th Edition)
Concepts of Genetics (12th Edition)
12th Edition
ISBN: 9780134604718
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
Publisher: PEARSON
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Chapter 19, Problem 1PDQ

(a)

Summary Introduction

To determine: The way in which methylation of promoters silences gene expression.

Introduction: Methylation can be defined as the process of adding on a methyl group to a molecule of DNA. The process of methylation results in the modification of DNA activity, but it does not change the DNA sequence.

(b)

Summary Introduction

To determine: The evidence that epigenetic changes are involved in cancer.

Introduction: Epigenetics refers to the study of alteration in the expression of genes. The changes in gene expression do not alter the DNA sequence that is only the phenotype is altered without alteration in the genotype.

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