EP CONNECT ONLINE ACCESS FOR BIOLOGY
EP CONNECT ONLINE ACCESS FOR BIOLOGY
20th Edition
ISBN: 9781260494655
Author: Raven
Publisher: MCG COURSE
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Chapter 19, Problem 1DA

What type of cells would develop if you injected embryos with a reagent that blocked the FGF receptor, thus preventing its signaling? What about with a reagent that turned on the FGF receptor, thereby causing it to be always on?

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Summary Introduction

To determine: The cells that would develop even after blocking FGF receptor and the effect on persistently active FGF receptor.

Introduction: Colony-stimulating factors (CSF) are the molecules that are a combination of polysaccharide and protein; thus, called glycoproteins. These are the factors that help in stimulating the production, proliferation and differentiation of various types of blood cells in the body.

Explanation of Solution

The different cells of the body undergo diverse cell fate due to molecule signalling and decision-making. The FGF (fibroblast growth factor) receptor is important protein receptor that regulates the growth of fibroblasts. The cells that will keep on dividing and differentiating after adding a reagent that blocks FGF receptor are the muscle precursor cells and nerve cord precursor cells. This is because the muscle precursor cells and nerve cord precursor cells do not have FGF receptor, and therefore its blocking willnot affect its functioning. On adding a reagent that persistently activates FGF receptor or over activates it can result in the various pathological conditions like unregulated cell growth, tumour genesis, and skeletal abnormalities like achondroplasia and craniosynostosis.

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After you feel comfortable with your counting method and identifying cells in the various stages of mitosis, use the four images below of whitefish blastula to count the cells in each stage until you reach 100 total cells, recording your data below in Data Table 1. (You may not need to use all four images. Stop counting when you reach 100 total cells.) After totaling the cells in each stage, calculate the percent of cells in each stage. (Divide total of stage by overall total of 100 and then multiply by 100 to obtain percentage.)   Data Table 1Stage    Totals    PercentInterphase        Mitosis:        Prophase        Metaphase        Anaphase        Telophase        Cytokinesis        Totals    100    100% To find the length of time whitefish blastula cells spend in each stage, multiply the percent (recorded as a decimal, in other words take the percent number and divide by 100) by 24 hours. (Example: If percent is 20%, then Time in Hours = .2 * 24 = 4.8) Record your data in Data…
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