Concept explainers
If you suspected that heterozygous carriers of a particular disease gene had a selective advantage in resisting a type of infection, how would you go about testing that hypothesis?
To determine: The way for testing of the hypothesis that the heterozygous carriers of a particular disease may have a differential advantage in resisting a particular type of infection.
Introduction: Allele refers to a pair of genes present on a chromosome. Alleles can exist as homozygous or heterozygous pairs. Heterozygous is a term used when different alleles of particular genes are present.
Explanation of Solution
Genetic testing will help in gathering information or evidence concerning the hypothesis that the frequency of an allele of a specific genome is advantageous over the other in a given population.
In order to find out whether a particular gene is responsible for causing disease, has an advantage over the other, genetic testing is performed. In this type of testing, various samples of both the indigenous and non-indigenous population are collected and analyzed. The survival rate and reproduction rate of both of the populations are analyzed.
Another way is to conduct experiments on model organisms that are heterozyogous and homozygous carriers. Expose the heterozygous and homozygous carriers of both the populations to a particular disease, and then analyze both the groups for their survival and reproduction rates.
Hence, genetic testing and experimentation on model organisms are ways for testing the hypothesis that heterozygous carriers for a specific disease had a selective advantage in infection certain type of infection.
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Chapter 19 Solutions
Human Heredity: Principles and Issues (MindTap Course List)
- You are testing whether or not there is a difference between the weights of healthy mice, and those infected with the mouse equivalent of COVID-19. You notice that the sick mice tend to have lower weight. To see if this is statistically significant, you run a t-test. What are your null and alternative hypotheses? Choose the best answer. O a. Null: Slck mice have lower weights than healthy mice; Alternative: There is no difference between the groups O b. Null: There is no difference between the groups; Alternative: There is a difference between the groups c. Null: Sick mice have higher weights than healthy mice; Alternative: Sick mice have lower weights than healthy mice O d. There is no difference between the groups; Alternative: Sick mice have higher weights than healthy micearrow_forwardPenicillin was first used in the 1940s to treat gonorrhea infections produced by the bacterium Neisseria gonorrhoeae. In 1984, according to the CDC, fewer than 1% of gonorrhea infections were caused by penicillin-resistant N. gonorrhoeae. By 1990, more than 10% of cases were penicillin resistant and a few years later the level of resistance was 95%. Explain the various ways this resistance could be spread among the cells. Could this resistance pass to other infectious bacteria from N. gonorrhoeae?arrow_forwardIn the 1940s, the U.S. government was looking for a solution to a medical problem: the prevalence of sexually transmitted diseases (STDs) among soldiers. Several now-infamous government-funded studies used human subjects to research common STDs and treatments. In one such study, American researchers intentionally exposed more than 1300 human subjects in Guatemala to syphilis, gonorrhea, and chancroid to determine the ability of penicillin and other antibiotics to combat these diseases. Subjects of the study included Guatemalan soldiers, prisoners, prostitutes, and psychiatric patients—none of whom were informed that they were taking part in the study. 1) What type of Epidemiological Study does this fall under; Descriptive, Analytical, Retrospective, Observational, or Prospective. 2) Please explain why this study was ethical or unethical. 3) We discussed a similar tragic but famous study that happened in the U.S. (it took place in Alabama) in one of our lectures. What was the name and…arrow_forward
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- Human Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage Learning