GEN COMBO LOOSELEAF MICROBIOLOGY:A SYSTEMS APPROACH; CONNECT ACCESS CARD
GEN COMBO LOOSELEAF MICROBIOLOGY:A SYSTEMS APPROACH; CONNECT ACCESS CARD
5th Edition
ISBN: 9781260149364
Author: Marjorie Kelly Cowan Professor
Publisher: McGraw-Hill Education
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Chapter 19, Problem 1CM
Summary Introduction

To construct:

A concept map illustrating relationships among bacteria, viruses, fungi, droplets, vehicles, vaccines, meningitis, colonization, transmission, and vaccination.

Concept introduction:

The concept map can be defined as the diagram which depicts the relationship between different concepts. This is particularly used for organizing and structuring knowledge. It is comprised of the information that is represented in circles or boxes and they are interlinked with the labeled arrows.

Meningitis is a type of acute inflammation that mainly occurs in the membrane of the brain and spinal cord. Its symptoms are a stiff neck, rash, vomiting, dislike lights, confusion, seizures, and headache. Bacterial meningitis is more fatal than viral meningitis.

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You aim to test the hypothesis that the Tbx4 and Tbx5 genes inhibit each other's expression during limb development. With access to chicken embryos and viruses capable of overexpressing Tbx4 and Tbx5, describe an experiment to investigate whether these genes suppress each other's expression in the limb buds. What results would you expect if they do repress each other? What results would you expect if they do not repress each other?
You decide to delete Fgf4 and Fgf8 specifically in the limb bud. Explain why you would not knock out these genes in the entire embryo instead.
You implant an FGF10-coated bead into the anterior flank of a chicken embryo, directly below the level of the wing bud. What is the phenotype of the resulting ectopic limb?  Briefly describe the expected expression domains of 1) Shh, 2) Tbx4, and 3) Tbx5 in the resulting ectopic limb bud.
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