Chapter 19, Problem 19.42P

Interpretation Introduction

(a)

Interpretation:

If the given compound must be synthesized using compounds with six or fewer carbons, it is to be determined which carbon–carbon bond-forming reaction from Table 19-1 should be incorporated in the synthesis.

Concept introduction:

The carbon–carbon bond-forming reaction results in heteroatoms having a specific relative positioning along the carbon backbone. If the heteroatoms in a target have 1, 2-, 1, 3-, 1, 4-, or 1, 5- relative positioning and the synthesis calls for a carbon–carbon bond-forming reaction, then consider using a corresponding reaction from Table 19-1. In a retrosynthetic analysis, therefore, apply a transform that takes our target molecule back to reactants. Disconnect the appropriate C-C bond to take back to reactants.

Interpretation Introduction

(b)

Interpretation:

If the given compound must be synthesized using compounds with six or fewer carbons, it is to be determined which carbon–carbon bond-forming reaction from Table 19-1 should be incorporated in the synthesis.

Concept introduction:

The carbon–carbon bond-forming reaction results in heteroatoms having a specific relative positioning along the carbon backbone. If the heteroatoms in a target have 1, 2-, 1, 3-, 1, 4-, or 1, 5- relative positioning and the synthesis calls for a carbon–carbon bond-forming reaction, then consider using a corresponding reaction from Table 19-1. In a retrosynthetic analysis, therefore, apply a transform that takes our target molecule back to reactants. Disconnect the appropriate C-C bond to take back to reactants.

Interpretation Introduction

(c)

Interpretation:

If the given compound must be synthesized using compounds with six or fewer carbons, it is to be determined which carbon–carbon bond-forming reaction from Table 19-1 should be incorporated in the synthesis.

Concept introduction:

The carbon–carbon bond-forming reaction results in heteroatoms having a specific relative positioning along the carbon backbone. If the heteroatoms in a target have 1, 2-, 1, 3-, 1, 4-, or 1, 5- relative positioning and the synthesis calls for a carbon–carbon bond-forming reaction, then consider using a corresponding reaction from Table 19-1. In a retrosynthetic analysis, therefore, apply a transform that takes our target molecule back to reactants. Disconnect the appropriate C-C bond to take back to reactants.

Interpretation Introduction

(d)

Interpretation:

If the given compound must be synthesized using compounds with six or fewer carbons, it is to be determined which carbon–carbon bond-forming reaction from Table 19-1 should be incorporated in the synthesis.

Concept introduction:

The carbon–carbon bond-forming reaction results in heteroatoms having a specific relative positioning along the carbon backbone. If the heteroatoms in a target have 1, 2-, 1, 3-, 1, 4-, or 1, 5- relative positioning and the synthesis calls for a carbon–carbon bond-forming reaction, then consider using a corresponding reaction from Table 19-1. In a retrosynthetic analysis, therefore, apply a transform that takes our target molecule back to reactants. Disconnect the appropriate C-C bond to take back to reactants.