The given statement “We would have no idea today of the importance of insulin as a regulatory hormone if its absence was not associated with the devastating human disease diabetes. It is the dramatic consequences of its absence that focused early efforts on the identification of insulin and the study of its normal role in physiology”. Concept introduction: An important hormone that is used to maintain the blood glucose level is called insulin. It is produced in the islets of Langerhans in pancreas. The structure of insulin contains mainly two peptide chains namely A chain and B chain. An insulin molecule is made up of 51 amino acids. The A chain contains 21 amino acids, while the B chain contains 30 amino acids, and they are joined together by two disulfide bonds. The condition where the insulin is absent or limited to control the level of sugar in the body, a condition known as diabetes mellitus.

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Chapter 19, Problem 17Q

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To discuss: The given statement “We would have no idea today of the importance of insulin as a regulatory hormone if its absence was not associated with the devastating human disease diabetes. It is the dramatic consequences of its absence that focused early efforts on the identification of insulin and the study of its normal role in physiology”.

Concept introduction: An important hormone that is used to maintain the blood glucose level is called insulin. It is produced in the islets of Langerhans in pancreas. The structure of insulin contains mainly two peptide chains namely A chain and B chain. An insulin molecule is made up of 51 amino acids. The A chain contains 21 amino acids, while the B chain contains 30 amino acids, and they are joined together by two disulfide bonds. The condition where the insulin is absent or limited to control the level of sugar in the body, a condition known as diabetes mellitus.

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