The activity of RNA polymerase II is inhibited by Actinomycin D. When actinomycin D is present, early development in many vertebrate species, for example frogs, can begin after the formation of a blastula (hollow ball of cells that forms after early cleavage divisions), but development stops before gastrulation. Question asked to discuss the activity of maternal gene in contrast to activity of zygotic gene in early frog development. Introduction: Drosophila is the model organism of study of development. It is a well studied genome sequence. Multiple genes are involved in the development of drosophila. The gene that directs the development and fate of an organism are known as developmental genes. Bicoid and Nanos are maternal effect genes; the egg receives these from the mother. Bicoid and Nanos play an important role in creating the anterior to posterior axis. The genes are activated in the fertilized egg (Zygote). In contrast to maternal effect genes, these genes are transcribed by zygotic DNA.

Question

Want to see the full answer?

Answer 1

Question

Chapter 18, Problem 9P

Summary Introduction

To analyze:

The activity of RNA polymerase II is inhibited by Actinomycin D. When actinomycin D is present, early development in many vertebrate species, for example frogs, can begin after the formation of a blastula (hollow ball of cells that forms after early cleavage divisions), but development stops before gastrulation. Question asked to discuss the activity of maternal gene in contrast to activity of zygotic gene in early frog development.

Introduction:

Drosophila is the model organism of study of development. It is a well studied genome sequence. Multiple genes are involved in the development of drosophila. The gene that directs the development and fate of an organism are known as developmental genes. Bicoid and Nanos are maternal effect genes; the egg receives these from the mother. Bicoid and Nanos play an important role in creating the anterior to posterior axis. The genes are activated in the fertilized egg (Zygote). In contrast to maternal effect genes, these genes are transcribed by zygotic DNA.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

From your previous experiment, you found that this enhancer activates stripe 2 of eve expression. When you sequence this enhancer you find several binding sites for the gap gene, Giant. To test how Giant interacts with eve, you decide to remove all of the Giant binding sites from the eve enhancer. What results do you expect to see with respect to eve expression?

What experiment could you do to see if the maternal gene, bicoid, is sufficient to form anterior fates?

You’re curious about the effect that gap genes have on the pair-rule gene, evenskipped (eve), so you isolate and sequence each of the eve enhancers. You’re particularly interested in one of the enhancers, which is just upstream of the eve gene. Describe an experimental technique you would use to find out where this particular eve enhancer is active.